SCHEMBL3378787

SCHEMBL3378787

CC(=O)c1cccc(N)c1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.67
ALDH1A1 P00352 5/20 0.44
HSD17B10 Q99714 4/20 0.44
CFTR P13569 1/20 0.44
THRB P10828 1/20 0.41
KDM4E B2RXH2 4/20 0.41
MAPT P10636 3/20 0.41
MEN1 O00255 1/20 0.41
NSD2 O96028 1/20 0.41
POLB P06746 1/20 0.41
KMT2A Q03164 1/20 0.41
MCL1 Q07820 1/20 0.41
BRD4 O60885 1/20 0.41
HPGD P15428 2/20 0.41
G6PD P11413 1/20 0.41
CASP7 P55210 1/20 0.41
CASP6 P55212 1/20 0.41
GAA P10253 1/20 0.41
FADS1 O60427 1/20 0.38
BRPF1 P55201 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6950003 0.98 MMP2 (0.64) MMP2ALDH1A1HSD17B10CFTRTHRB
Bromide SCHEMBL7636378 0.98 MMP2 (0.64) MMP2ALDH1A1HSD17B10CFTRTHRB
SCHEMBL7301332 0.84 THRB (0.50) MMP2ALDH1A1HSD17B10THRBKDM4E
SCHEMBL720049 0.82 MMP2 (0.72) MMP2ALDH1A1HSD17B10CFTRKDM4E
SCHEMBL505381 0.80 MMP2 (0.47) MMP2ALDH1A1HSD17B10CFTRTHRB
SCHEMBL29547161 0.80 MMP2 (1.00) MMP2ALDH1A1HSD17B10KDM4EMAPT
SCHEMBL204392 0.80 MMP2 (1.00) MMP2ALDH1A1HSD17B10KDM4EMAPT
SCHEMBL2019650 0.80 MMP2 (0.69) MMP2ALDH1A1HSD17B10CFTRKDM4E
2-Aminoacetophenone SCHEMBL29366456 0.79 ALDH1A1 (0.59) MMP2ALDH1A1HSD17B10CFTRKDM4E
2-Aminoacetophenone SCHEMBL309044 0.79 ALDH1A1 (0.59) MMP2ALDH1A1HSD17B10CFTRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063344-B Asymmetric enhanced acylhydrazone Schiff base fluorescent probe, preparation method and application XI'AN SHIYOU UNIVERSITY (CN) 2026-05-26 CN claimed
CN-119039327-A Symmetrical multidentate Schiff base trinuclear rare earth complex, preparation method and application 西安石油大学 2024-11-29 CN claimed
CN-119039328-A Butterfly-shaped trinuclear Schiff base rare earth metal catalyst, preparation method and application 西安石油大学 2024-11-29 CN claimed
CN-118950096-A Hourglass-shaped rare earth metal catalyst, preparation method and application 西安石油大学 2024-11-15 CN claimed
CN-118955323-A Used for Al3+Naphthalene schiff base fluorescent probe for detection, preparation method and application 西安石油大学 2024-11-15 CN claimed
CN-118955325-A Enhanced single Schiff base fluorescent probe, preparation method and application 西安石油大学 2024-11-15 CN claimed
CN-118878431-A Preparation method of 3-amino-2-hydroxyacetophenone 诚弘制药(威海)有限责任公司 2024-11-01 CN claimed
CN-118206483-A Enhanced acylhydrazone Schiff base fluorescent probe, preparation method and application 西安石油大学 2024-06-18 CN claimed
CN-118206572-A Trinuclear dysprosium single-molecule magnet based on acylhydrazone Schiff base and preparation method 西安石油大学 2024-06-18 CN claimed
CN-118063344-A Asymmetric enhanced acylhydrazone Schiff base fluorescent probe, preparation method and application 西安石油大学 2024-05-24 CN claimed
CN-110437463-B Dendritic polymer, preparation method and application thereof 威海晨源分子新材料有限公司 2022-01-21 CN claimed
CN-107098822-B Preparation method for pranlukast key intermediate 3-amino-2-hydroxyacetophenone 上海微巨实业有限公司 2021-05-28 CN claimed
CN-212081779-U Cooling device for preparing 3-amino-2-hydroxyacetophenone 上海微巨实业有限公司 2020-12-04 CN claimed
CN-111960957-A Preparation method of pranlukast intermediate 太仓康源化建医药有限公司 2020-11-20 CN claimed
CN-106366310-B Carboxyl-containing high-refractive-index hyperbranched polyesteramide, preparation method thereof and application thereof in plastic modification 威海晨源分子新材料有限公司 2020-09-08 CN claimed
CN-107698452-B Synthetic method of 3-amino-2-hydroxyacetophenone 黑龙江鑫创生物科技开发有限公司 2020-06-02 CN claimed
CN-110437463-A Dendritic, preparation method and its application WEIHAI CY DENDRIMER TECH CO LTD 2019-11-12 CN claimed
CN-106366310-A Carboxyl-containing high-refractive-index hyperbranched polyesteramide and preparation method thereof, as well as application of carboxyl-containing high-refractive-index hyperbranched polyesteramide to plastic modification 威海晨源分子新材料有限公司 2017-02-01 CN claimed
US-7364881-B1 Biological process for the conversion of nitroarenes to ortho-aminophenols using recombinant E. coli strains UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2008-04-29 US claimed
US-5679859-A TREATING 3-AMINO-2-HYDROXYACETOPHENONE OR HYDROGEN HALIDE SALT THEREOF WITH SULFURIC ACID IN SOLVENT TO IMPROVE BULK DENSITY AND FLOW PROPERTIES SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1997-10-21 US claimed