SCHEMBL505381

SCHEMBL505381

CC(=O)c1cccc(N)c1N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.47
ALDH1A1 P00352 6/20 0.45
HSD17B10 Q99714 5/20 0.45
CFTR P13569 1/20 0.45
CD44 P16070 1/20 0.44
BRD4 O60885 1/20 0.42
MAPT P10636 2/20 0.42
G6PD P11413 1/20 0.42
CASP7 P55210 1/20 0.42
CASP6 P55212 1/20 0.42
GAA P10253 1/20 0.42
KDM4E B2RXH2 4/20 0.40
HPGD P15428 1/20 0.40
FADS1 O60427 1/20 0.39
TSHR P16473 2/20 0.39
CYP3A4 P08684 1/20 0.39
PIK3CA P42336 1/20 0.39
THRB P10828 1/20 0.38
LMNA P02545 1/20 0.38
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2647010 0.98 MMP2 (0.45) MMP2ALDH1A1HSD17B10CFTRCD44
SCHEMBL3498784 0.88 G6PD (0.46) MMP2ALDH1A1HSD17B10CFTRBRD4
Acetic Acid SCHEMBL27738534 0.83 G6PD (0.59) MMP2ALDH1A1HSD17B10CFTRCD44
SCHEMBL3784979 0.82 BRD4 (0.51) MMP2ALDH1A1HSD17B10CFTRBRD4
2-Aminoacetophenone SCHEMBL29366456 0.81 ALDH1A1 (0.59) MMP2ALDH1A1HSD17B10CFTRBRD4
SCHEMBL686612 0.81 MAPT (0.50) MMP2ALDH1A1HSD17B10CFTRCD44
2-Aminoacetophenone SCHEMBL309044 0.81 ALDH1A1 (0.59) MMP2ALDH1A1HSD17B10CFTRBRD4
Questiomycin B SCHEMBL27581895 0.81 G6PD (0.56) MMP2ALDH1A1HSD17B10CFTRBRD4
SCHEMBL704587 0.80 CD44 (0.48) ALDH1A1HSD17B10CD44G6PDCASP7
SCHEMBL3378787 0.80 MMP2 (0.67) MMP2ALDH1A1HSD17B10CFTRBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12269922-B2 Method for preparing aramid nanofiber dispersion KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2025-04-08 US disclosed
US-11846047-B2 Cloth and protective product TEIJIN LIMITED (JP) 2023-12-19 US disclosed
US-20230365707-A1 NUCLEIC ACIDS ENCODING HUMAN ANTIBODIES TO SIALYL-LEWIS A BioNTech SE (DE) 2023-11-16 US disclosed
US-20230322721-A1 TRIAZOLE DERIVATIVES AND THEIR USE AS TANKYRASE INHIBITORS UNIVERSITY OF OULU (FI) 2023-10-12 US disclosed
EP-3901339-B1 CLOTH AND PROTECTIVE PRODUCT TEIJIN LTD (JP) 2023-07-05 EP disclosed
EP-3440951-B1 FABRIC, MULTILAYER STRUCTURED FABRIC, AND FIBER PRODUCT TEIJIN LTD (JP) 2023-02-15 EP disclosed
US-20220408864-A1 FABRIC AND PROTECTIVE PRODUCT TEIJIN LIMITED (JP) 2022-12-29 US disclosed
US-20220325445-A1 FIREPROOF FABRIC AND SEAT TEIJIN LIMITED (JP) 2022-10-13 US disclosed
EP-4063547-A1 FABRIC AND PROTECTIVE PRODUCT Teijin Limited (JP) 2022-09-28 EP disclosed
US-20220259800-A1 DYED FABRIC, FIBER PRODUCT IN WHICH SAME IS USED, AND METHOD FOR DYEING FABRIC TEIJIN LIMITED (JP) 2022-08-18 US disclosed
EP-0036522-B1 WATER-SOLUBLE NICKEL-CONTAINING AZOPHTHALOCYANINE DYESTUFFS AND THEIR USE BASF Aktiengesellschaft (DE) 1983-11-16 EP disclosed
US-4389521-A AROMATIC POLYAMIDE TEIJIN LIMITED (JP) 1983-06-21 US disclosed
EP-0008126-B1 AROMATIC POLYAMIDE COMPOSITION TEIJIN LIMITED (JP) 1982-12-29 EP disclosed
EP-0036522-A2 Water-soluble nickel-containing azophthalocyanine dyestuffs and their use BASF Aktiengesellschaft (DE) 1981-09-30 EP disclosed
US-4250073-A HIGH CONCENTRATION OF POLYMER POSSIBLE; FILAMENTS AND FIBERS; GROUP 1A OR 2A METAL OR AMMONIUM HALIDE AS A SOLUBILITY-ENHANCING AGENT TEIJIN LIMITED (JP) 1981-02-10 US disclosed
EP-0008126-A1 Aromatic polyamide composition TEIJIN LIMITED (JP) 1980-02-20 EP disclosed
US-4138572-A Malonanilic derivatives ROUSSEL UCLAF (FR) 1979-02-06 US disclosed
US-4009154-A Process for preparing aromatic polyamides with sodium carbonate hydrate as acid acceptor TEIJIN LIMITED (JA) 1977-02-22 US disclosed
US-4001408-A SUBSTITUTED HETEROCYCLIC COMPOUNDS, PROCESSES AND COMPOSITION INCLUDING THOSE ROUSSEL-UCLAF (FR) 1977-01-04 US disclosed
US-3984398-A 1,5-Benzodiazepine-2,4-diones ROUSSEL-UCLAF (FR) 1976-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230322721-A1 TRIAZOLE DERIVATIVES AND THEIR USE AS TANKYRASE INHIBITORS CBR3, GBA3, TECR MMP2 2101/4885ALDH1A1 2476/4885HSD17B10 2947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.