Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902720 | 0.88 | DPP4 (0.39) | DPP4DPP8DPP9LMNAMAPT | |
| SCHEMBL7916793 | 0.88 | DPP4 (0.39) | DPP4DPP8DPP9LMNAMAPT | |
| SCHEMBL3433258 | 0.83 | DPP4 (0.38) | DPP4DPP8DPP9LMNAMAPT | |
| SCHEMBL3379679 | 0.80 | DHFR (0.38) | DPP4DPP8DPP9LMNAMAPT | |
| SCHEMBL3380430 | 0.79 | MAOB (0.38) | DPP4DPP8DPP9LMNAMAPT | |
| SCHEMBL3380282 | 0.78 | CYP3A4 (0.39) | RAB9AMAOBCYP2C9CYP2C19 | |
| SCHEMBL3380528 | 0.77 | PDE4D (0.60) | LMNAMAPTKMT2AALDH1A1CYP1A2 | |
| SCHEMBL3378785 | 0.75 | GABRA2 (0.47) | MAPTSMN1; SMN2KMT2ARAB9AKDM4E | |
| SCHEMBL3381952 | 0.74 | MAPK14 (0.43) | KMT2AKDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3380717 | 0.72 | PIK3CD (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059836-A1 | SUBSTITUTED AZA-BRIDGED BICYCLICS FOR CARDIOVASCULAR AND CNS DISEASE | DECODE GENETICS EHF (IS) | 2010-05-27 | — | — | WO | disclosed |