Piperidine

Piperidine

SCHEMBL3379742

C1CCNCC1.O=C(O)N1CC(O)C(O)C(Br)C1

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.31
CHKA P35790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL738604 0.74
SCHEMBL1867805 0.73 ALDH1A1 (0.42)
SCHEMBL665659 0.67
SCHEMBL3184989 0.67
SCHEMBL6098670 0.67
SCHEMBL1668760 0.67
Pyrrolidine SCHEMBL10794930 0.67 CA2 (0.58) CA2CHKA
Piperidine SCHEMBL4577836 0.62 ALDH1A1 (0.64) CA2CHKA
Azepane SCHEMBL714889 0.62 ALDH1A1 (0.64) CA2CHKA
Piperidine SCHEMBL720107 0.62 ALDH1A1 (0.64) CA2CHKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010049678-A2 TREATMENT OF ENERGY UTILIZATION DISEASES SUMMIT CORPORATION PLC (GB) 2010-05-06 WO disclosed