Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL29094370 | 0.88 | MMP2 (0.57) | MMP2CDC25BG6PDCASP7CASP6 | |
| SCHEMBL3502815 | 0.88 | THRB (0.46) | MMP2CDC25BG6PDCASP7CASP6 | |
| SCHEMBL48723 | 0.85 | MMP2 (0.63) | MMP2CDC25BG6PDCASP7CASP6 | |
| SCHEMBL15869337 | 0.85 | MMP2 (0.63) | MMP2CDC25BG6PDCASP7CASP6 | |
| SCHEMBL27925721 | 0.85 | MMP2 (0.63) | MMP2CDC25BG6PDCASP7CASP6 | |
| SCHEMBL29367294 | 0.85 | MMP2 (0.63) | MMP2CDC25BG6PDCASP7CASP6 | |
| SCHEMBL15049648 | 0.85 | ALDH1A1 (0.55) | MMP2G6PDCASP7CASP6HSD17B10 | |
| SCHEMBL31024653 | 0.84 | MMP2 (0.52) | MMP2CDC25BG6PDCASP7CASP6 | |
| SCHEMBL7833293 | 0.84 | MMP2 (0.52) | MMP2CDC25BG6PDCASP7CASP6 | |
| SCHEMBL8070939 | 0.83 | MMP2 (0.61) | MMP2CDC25BG6PDCASP7CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010062959-A1 | 5-HT4 RECEPTOR AGONISTS FOR TREATING IRRITABLE BOWEL SYNDROME AND COLONIC HYPERSENSITIVITY | ARYX THERAPEUTICS, INC. (US) | 2010-06-03 | — | — | WO | claimed |
| EP-2707224-B1 | POLYMER COMPOSITIONS AND METHODS | SAUDI ARAMCO TECH CO (SA) | 2017-10-25 | — | — | EP | disclosed |
| CN-105658229-A | Compounds, compositions and methods for the treatment of diseases through inhibiting TGF-beta activity | 南方研究所 | 2016-06-08 | — | — | CN | disclosed |
| CN-103889963-B | The similar thing of quinazolinone and the similar thing of quinazolinone are being used for the treatment of or are preventing the application in some virus infection | SOUTHERN RESEARCH INSTITUTE (US) | 2016-01-20 | — | — | CN | disclosed |
| CN-102822192-B | Pyruvamide compounds as inhibitors of dust mite group 1 peptidase allergen | ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) | 2015-09-30 | — | — | CN | disclosed |
| CN-103694161-B | The manufacture method of pharmaceutically active agents | H. LUNDHECK A/S (DK) | 2015-09-09 | — | — | CN | disclosed |
| CN-104471058-A | Compositions comprising chalcogenides and related methods | HUTCHINSON FRED CANCER RES | 2015-03-25 | — | — | CN | disclosed |
| CN-102269932-B | Radiation-sensitive resin composition, cured film and forming method thereof and display element | JSR CORP | 2015-03-25 | — | — | CN | disclosed |
| CN-104395317-A | Heterocycle-fused morphinans, use thereof and preparation thereof | SOUTHERN RES INST | 2015-03-04 | — | — | CN | disclosed |
| CN-102656146-B | Process for the manufacture of pharmaceutically active agents | LUNDBECK & CO AS H | 2014-12-17 | — | — | CN | disclosed |
| CN-1237598-A | Hollow sphere organic pigment for paper or paper coating | ROHM & HAAS (US) | 1999-12-08 | — | — | CN | disclosed |
| CN-1230957-A | Process for synthesis of benzothiophenes | LILLY CO ELI (US) | 1999-10-06 | — | — | CN | disclosed |
| CN-1180353-A | Process for preparing 2-substituted benzo [ b ] thiophenes and intermediates thereof | LILLY CO ELI (US) | 1998-04-29 | — | — | CN | disclosed |
| CN-1157822-A | Pharmaceutical compounds | LILLY INDUSTRIES LTD (GB) | 1997-08-27 | — | — | CN | disclosed |
| CN-1137525-A | Naphthyl compounds, intermediates, compositions and methods | LILLY CO ELI (US) | 1996-12-11 | — | — | CN | disclosed |
| CN-1130634-A | Encapsulated hydrophilic polymers and their preparation | ROHM & HAAS (US) | 1996-09-11 | — | — | CN | disclosed |
| CN-1109884-A | Methods of inhibiting myeloperoxidase activity | LILLY CO ELI (US) | 1995-10-11 | — | — | CN | disclosed |
| CN-1108255-A | Methods of inhibiting the symtoms of premenstrual syndrome/late luteal phase dysphoric disorder | LILLY CO ELI (US) | 1995-09-13 | — | — | CN | disclosed |
| CN-1107157-A | Methods for the treatment of peri-menopausal syndrome | LILLY CO ELI (US) | 1995-08-23 | — | — | CN | disclosed |
| CN-1105359-A | Methods for inhibiting smooth muscle cell proliferation and restinosis | LILLY CO ELI (US) | 1995-07-19 | — | — | CN | disclosed |