SCHEMBL29367294

SCHEMBL29367294

Nc1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.63
G6PD P11413 1/20 0.52
CASP7 P55210 1/20 0.52
CASP6 P55212 1/20 0.52
ALDH1A1 P00352 3/20 0.50
ALOX15 P16050 1/20 0.50
CDC25B P30305 2/20 0.47
MAPT P10636 2/20 0.47
GAA P10253 1/20 0.47
NAPRT Q6XQN6 2/20 0.45
IDO1 P14902 1/20 0.45
AKR1C3 P42330 1/20 0.45
KDM4E B2RXH2 3/20 0.45
HSD17B10 Q99714 2/20 0.45
NPC1 O15118 1/20 0.45
CASP3 P42574 1/20 0.45
RAB9A P51151 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48723 1.00 MMP2 (0.63) MMP2G6PDCASP7CASP6ALDH1A1
SCHEMBL27925721 1.00 MMP2 (0.63) MMP2G6PDCASP7CASP6ALDH1A1
SCHEMBL15869337 1.00 MMP2 (0.63) MMP2G6PDCASP7CASP6ALDH1A1
SCHEMBL26108766 0.98 MMP2 (0.61) MMP2G6PDCASP7CASP6ALDH1A1
SCHEMBL28508112 0.98 MMP2 (0.61) MMP2G6PDCASP7CASP6ALDH1A1
Hydrochloric Acid SCHEMBL2285638 0.98 MMP2 (0.61) MMP2G6PDCASP7CASP6ALDH1A1
Hydrazine SCHEMBL28369279 0.98 MMP2 (0.61) MMP2G6PDCASP7CASP6ALDH1A1
SCHEMBL8070950 0.98 MMP2 (0.61) MMP2G6PDCASP7CASP6ALDH1A1
SCHEMBL8070939 0.98 MMP2 (0.61) MMP2G6PDCASP7CASP6ALDH1A1
Hydrochloric Acid SCHEMBL28051606 0.96 MMP2 (0.59) MMP2G6PDCASP7CASP6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598969-A1 FUNCTIONALIZED MACROMOLECULES AND SYSTEMS, METHODS OF SYNTHESIS, AND USES THEREOF Seer, Inc. (US) 2025-08-13 EP claimed
EP-3619195-B1 NOVEL PROCESS TO PREPARE N-[2-[(1S)-1-(3-ETHOXY-4-METHOXYPHENYL)-2-(METHYLSULPHONYL) ETHYL]-1, 3-DIOXO-2,3-DIHYDRO-1H-ISOINDOL-4-YL]ACETAMIDE UNICHEM LAB LTD (IN) 2025-07-23 EP claimed
WO-2025101535-A1 BIOMOLECULE CLEANUP METHODS, KITS, AND SYSTEMS SEER, INC. (US) 2025-05-15 WO claimed
US-20240384002-A1 METHODS FOR SITE SPECIFIC CONJUGATION OF PROTEINS CONTAINING GLYCOSYLATED Fc DOMAINS JANSSEN BIOTECH, INC. 2024-11-21 US claimed
US-12084475-B2 Methods for site specific conjugation of proteins containing glycosylated Fc domains JANSSEN BIOTECH, INC. (US) 2024-09-10 US claimed
WO-2024077009-A1 FUNCTIONALIZED MACROMOLECULES AND SYSTEMS, METHODS OF SYNTHESIS, AND USES THEREOF SEER, INC. (US) 2024-04-11 WO claimed
CN-116887607-A Method for improving thermal stability of perovskite solar cell 河北工业大学 2023-10-13 CN claimed
US-20260133184-A1 OXIDASE-BASED CHEMILUMINESCENCE ASSAY OF PHAGOCYTIC LEUKOCYTES IN WHOLE BLOOD AND BODY FLUIDS APPLICABLE TO POINT-OF-CARE (POC) DIAGNOSTIC TESTING POINT-OF-CARE (POC) MEASUREMENT OF ABSOLUTE NEUTROPHIL FUNCTION (ANF) BINARY LLC (US) 2026-05-14 US disclosed
US-12624026-B2 Inhibitors of SARM1 DISARM THERAPEUTICS, INC. (US) 2026-05-12 US disclosed
US-12622944-B2 Compositions containing, methods involving, and uses of non-natural amino acid linked dolastatin derivatives AMBRX, INC. (US) 2026-05-12 US disclosed
US-12568986-B2 Method of reducing acrylamide in coffee extract and a soluble coffee product KONINKLIJKE DOUWE EGBERTS B.V. (NL) 2026-03-10 US disclosed
US-20260063624-A1 OXIDASE-BASED CHEMILUMINESCENCE ASSAY OF PHAGOCYTIC LEUKOCYTES IN WHOLE BLOOD AND BODY FLUIDS APPLICABLE TO POINT-OF-CARE (POC) DIAGNOSTIC TESTING POINT-OF-CARE (POC) MEASUREMENT OF ABSOLUTE NEUTROPHIL FUNCTION (ANF) BINARY LLC (US) 2026-03-05 US disclosed
US-20260056193-A1 FUNCTIONALIZED MACROMOLECULES AND SYSTEMS, METHODS OF SYNTHESIS, AND USES THEREOF SEER INC (US) 2026-02-26 US disclosed
US-11331020-B2 Enzyme-based electrochemical nicotine biosensor TRUSTEES OF BOSTON UNIVERSITY (US) 2022-05-17 US disclosed
EP-3990900-A1 OXIDASE-BASED CHEMILUMINESCENCE ASSAY OF PHAGOCYTIC LEUKOCYTES IN WHOLE BLOOD AND BODY FLUIDS APPLICABLE TO POINT-OF-CARE (POC) DIAGNOSTIC TESTING POINT-OF-CARE (POC) MEASUREMENT OF ABSOLUTE NEUTROPHIL FUNCTION (ANF) Binary LLC (US) 2022-05-04 EP disclosed
CN-108495563-B Nicotine salts, co-crystals and salt co-crystal complexes R.J.雷诺兹烟草公司 2022-04-26 CN disclosed
US-11260046-B2 (+)-2-[1-(3-Ethoxy-4- methoxyphenyl)-2-methylsulfonylethyl]- 4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof AMGEN INC. (US) 2022-03-01 US disclosed
US-20220047639-A1 Method of Preparing Hematopoietic Stem and Progenitor Cells for Transplantation THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2022-02-17 US disclosed
US-20220033518-A1 PROSTATE-SPECIFIC MEMBRANE ANTIGEN ANTIBODY DRUG CONJUGATES AMBRX,INC. (US) 2022-02-03 US disclosed
CN-114002207-A Application of ascorbic acid peroxidase 1 in catalysis of luminol chemiluminescence reaction 浙江大学 2022-02-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624026-B2 Inhibitors of SARM1 SARM1, SMN1; SMN2, NNMT MMP2 653/4885G6PD 3334/4885CASP7 2748/4885
US-20260063624-A1 OXIDASE-BASED CHEMILUMINESCENCE ASSAY OF PHAGOCYTIC LEUKOCYTES IN WHOLE BLOOD AND BODY FLUIDS APPLICABLE TO POINT-OF-CARE (POC) DIAGNOSTIC TESTING POINT-OF-CARE (POC) MEASUREMENT OF ABSOLUTE NEUTROPHIL FUNCTION (ANF) MPO, NOX3, NOX1 MMP2 702/4885G6PD 66/4885CASP7 487/4885
US-11260046-B2 (+)-2-[1-(3-Ethoxy-4- methoxyphenyl)-2-methylsulfonylethyl]- 4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof PDE4A, PDE4B, PDE2A MMP2 91/4885G6PD 499/4885CASP7 357/4885
US-20260056193-A1 FUNCTIONALIZED MACROMOLECULES AND SYSTEMS, METHODS OF SYNTHESIS, AND USES THEREOF CPS1, CA6, SMC2 MMP2 2449/4885G6PD 52/4885CASP7 4126/4885
US-12622944-B2 Compositions containing, methods involving, and uses of non-natural amino acid linked dolastatin derivatives DDOST, DMPK, KRTCAP2 MMP2 4048/4885G6PD 3430/4885CASP7 3737/4885
US-20260133184-A1 OXIDASE-BASED CHEMILUMINESCENCE ASSAY OF PHAGOCYTIC LEUKOCYTES IN WHOLE BLOOD AND BODY FLUIDS APPLICABLE TO POINT-OF-CARE (POC) DIAGNOSTIC TESTING POINT-OF-CARE (POC) MEASUREMENT OF ABSOLUTE NEUTROPHIL FUNCTION (ANF) MPO, MYADM, CD14 MMP2 1059/4885G6PD 71/4885CASP7 366/4885
US-20220033518-A1 PROSTATE-SPECIFIC MEMBRANE ANTIGEN ANTIBODY DRUG CONJUGATES KLK3, PTMS, DDOST MMP2 2979/4885G6PD 2060/4885CASP7 3451/4885
US-12568986-B2 Method of reducing acrylamide in coffee extract and a soluble coffee product ACR, ADCY10, CIP2A MMP2 888/4885G6PD 3746/4885CASP7 1106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.