Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 4/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381498 | 0.87 | PTGS2 (0.35) | PTGS2ADAMTS5CYP2C9PTGS1CYP2C19 | |
| SCHEMBL3384079 | 0.87 | PTGS2 (0.34) | PTGS2GRIA2ADAMTS5CYP2C9PTGS1 | |
| SCHEMBL3381612 | 0.81 | ADAMTS5 (0.33) | GRIA2ADAMTS5CYP2C9CYP2C19 | |
| SCHEMBL29169585 | 0.73 | GAA (0.33) | CYP2C9CYP2C19ALDH1A1CYP3A4GAA | |
| SCHEMBL14364493 | 0.73 | ALDH1A1 (0.34) | CYP2C9CYP2C19ALDH1A1CYP3A4GAA | |
| SCHEMBL13055879 | 0.73 | GAA (0.33) | CYP2C9CYP2C19ALDH1A1GAA | |
| SCHEMBL28573200 | 0.72 | GAA (0.33) | CYP2C9CYP2C19CYP3A4GAA | |
| SCHEMBL3736237 | 0.72 | ALDH1A1 (0.39) | CYP2C9CYP2C19ALDH1A1CYP3A4GAA | |
| SCHEMBL14364501 | 0.72 | GAA (0.33) | GAA | |
| SCHEMBL14364512 | 0.72 | GAA (0.32) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404618-B2 | Herbicidal composition | SYNGENTA LIMITED (GB) | 2013-03-26 | — | — | US | disclosed |
| EP-1364946-B1 | ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2010-11-24 | — | — | EP | disclosed |
| US-7833939-B2 | Herbicide compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| EP-2186410-A1 | Isoxazoline derivative and herbicide comprising the same as active ingredient | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-05-19 | — | — | EP | disclosed |
| US-20070259786-A1 | Herbicidal Composition | SYNGENTA CROP PROTECTION, INC. (US) | 2007-11-08 | — | — | US | disclosed |
| US-7238689-B2 | Isoxazoline derivative and herbicide comprising the same as active ingredient | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-07-03 | — | — | US | disclosed |
| US-20050256004-A1 | Herbicide compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
| US-20040110749-A1 | Isoxazoline derivative and herbicide comprising the same as active ingredient | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
| EP-1364946-A1 | ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259786-A1 | Herbicidal Composition | DDT, IDH2, ACHE | PTGS2 2993/4885GRIA2 1181/4885ADAMTS5 3134/4885 |
| US-20050256004-A1 | Herbicide compositions | DDT, CYP4X1, GLRX3 | PTGS2 3715/4885GRIA2 109/4885ADAMTS5 4264/4885 |
| US-20040110749-A1 | Isoxazoline derivative and herbicide comprising the same as active ingredient | CYP4X1, PRDX5, CYP3A7 | PTGS2 2491/4885GRIA2 412/4885ADAMTS5 4327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.