Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.69 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246063 | 1.00 | HCAR2 (0.69) | HCAR2ABCG2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL11721533 | 0.87 | HCAR2 (0.58) | HCAR2ABCG2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL4212112 | 0.84 | HCAR2 (0.96) | HCAR2ABCG2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL5598744 | 0.83 | HCAR2 (0.74) | HCAR2ABCG2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL5598741 | 0.83 | HCAR2 (0.74) | HCAR2ABCG2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1086015 | 0.82 | HCAR2 (0.71) | HCAR2ABCG2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL600082 | 0.82 | HCAR2 (1.00) | HCAR2ABCG2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL143282 | 0.82 | HCAR2 (1.00) | HCAR2ABCG2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL4197243 | 0.82 | HCAR2 (0.71) | HCAR2ABCG2SMN1; SMN2LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL9874572 | 0.80 | HCAR2 (0.96) | HCAR2ABCG2SMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114507211-B | Preparation method of 2, 3-naphthalimide derivative | 华中科技大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-114573502-A | Pleuromutilin aromatic heterocyclic acrylate compounds and synthesis method and application thereof | 西安康远晟生物医药科技有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-114507211-A | Preparation method of 2, 3-naphthalimide derivative | 华中科技大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-113912769-A | Temperature-resistant salt-tolerant gel foam system and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-01-11 | — | — | CN | disclosed |
| WO-2013173382-A1 | BENZOTHIOPHENE SULFONAMIDES AND OTHER COMPOUNDS THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN | AMGEN INC. (US) | 2013-11-21 | — | — | WO | disclosed |
| EP-1539675-B1 | ARYL AND HETEROARYL PROPENE AMIDES, DERIVATIVES THEREOF AND THERAPEUTIC USES THEREOF | UNIV TEMPLE (US) | 2013-11-06 | — | — | EP | disclosed |
| EP-1670779-B1 | METHODS FOR THE PRODUCTION OF 3-METHYLAMINO-1-(THIENE-2-YL)-PROPANE-1-OL | BASF SE (DE) | 2010-11-24 | — | — | EP | disclosed |
| US-7498448-B2 | Methods for the production of 3-methylamino-1-(thiene-2-yl)-propane-1-ol | BASF AKTIENGESELLSCHAFT (DE) | 2009-03-03 | — | — | US | disclosed |
| US-7482488-B2 | Aryl and heteroaryl propene amides, derivatives thereof and therapeutic uses thereof | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2009-01-27 | — | — | US | disclosed |
| EP-1614683-B1 | Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use | AGOURON PHARMA (US) | 2007-11-21 | — | — | EP | disclosed |
| EP-0156382-B1 | SEPARATION AGENT COMPRISING ACYL-OR CARBAMOYL-SUBSTITUTED POLYSACCHARIDE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |
| US-4879038-A | Separation agent comprising acyl- or carbamoyl-substituted polysaccharide | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| US-4677104-A | Antipsychotic fused-ring pyridinylpiperazine derivatives | BRISTOL-MYERS COMPANY (US) | 1987-06-30 | — | — | US | disclosed |
| EP-0079049-B1 | NOVEL SUBSTITUTED ALKANOYLIMIDAZOL-2-ONE DERIVATIVES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-04-01 | — | — | EP | disclosed |
| EP-0156382-A2 | Separation agent comprising acyl-or carbamoyl-substituted polysaccharide | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1985-10-02 | — | — | EP | disclosed |
| US-4447619-A | CARDIOTONIC AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-05-08 | — | — | US | disclosed |
| EP-0079049-A2 | Novel substituted alkanoylimidazol-2-one derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-05-18 | — | — | EP | disclosed |
| US-4367236-A | CARDIOTONIC AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-01-04 | — | — | US | disclosed |
| US-4264713-A | COMPRISING LIGHT SENSITIVE POLYMERS OF AN UNSATURATED POLYESTER AND AN ACRYLIC POLYMER WITH UNSATURATED SIDE CHAINS | FUJI PHOTO FILM CO., LTD. (JP) | 1981-04-28 | — | — | US | disclosed |
| US-3945831-A | Photosensitive resins containing a thienylacrylic acid ester or amide group | FUJI PHOTO FILM CO., LTD. (JA) | 1976-03-23 | — | — | US | disclosed |