SCHEMBL3382516

SCHEMBL3382516

COC(=O)c1ccccc1C(N)=O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.64
HSD17B10 Q99714 2/20 0.64
CFTR P13569 1/20 0.64
TSHR P16473 3/20 0.61
LMNA P02545 2/20 0.61
KDM4E B2RXH2 3/20 0.57
POLB P06746 1/20 0.57
ATM Q13315 1/20 0.57
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA5A P35218 1/20 0.56
CA9 Q16790 1/20 0.56
SIRT2 Q8IXJ6 1/20 0.56
MYC P01106 1/20 0.55
MAPT P10636 2/20 0.52
ALOX15 P16050 1/20 0.52
KMT2A Q03164 1/20 0.52
SLC6A3 Q01959 3/20 0.50
HPGD P15428 1/20 0.50
SLC6A4 P31645 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethyl Phthalate SCHEMBL28758679 0.89 ALDH1A1 (0.72) ALDH1A1HSD17B10CFTRTSHRLMNA
Dimethyl Phthalate SCHEMBL790124 0.89 TSHR (0.74) ALDH1A1HSD17B10CFTRTSHRLMNA
Dimethyl Phthalate SCHEMBL34630 0.89 TSHR (0.74) ALDH1A1HSD17B10CFTRTSHRLMNA
Dimethyl Phthalate SCHEMBL29669976 0.89 TSHR (0.74) ALDH1A1HSD17B10CFTRTSHRLMNA
Dimethyl Phthalate SCHEMBL29500970 0.89 TSHR (0.74) ALDH1A1HSD17B10CFTRTSHRLMNA
Dimethyl Phthalate SCHEMBL27305707 0.87 ALDH1A1 (0.64) ALDH1A1HSD17B10CFTRTSHRLMNA
Dimethyl Phthalate SCHEMBL10602130 0.86 TSHR (0.71) ALDH1A1HSD17B10CFTRTSHRLMNA
Dimethyl Phthalate SCHEMBL30278536 0.86 TSHR (0.71) ALDH1A1HSD17B10CFTRTSHRLMNA
Dimethyl Phthalate SCHEMBL28376050 0.86 TSHR (0.71) ALDH1A1HSD17B10CFTRTSHRLMNA
Dimethyl Phthalate SCHEMBL27547487 0.86 TSHR (0.71) ALDH1A1HSD17B10CFTRTSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102459251-A Compounds having two fused bicyclic heteroaryl moieties as modulators of leukotriene A4 hydrolase JANSSEN PHARMACEUTICA NV 2012-05-16 CN claimed
EP-1126833-A4 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES INC (US) 2004-09-08 EP claimed
EP-1150565-A1 THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION bioscience AG (DE) 2001-11-07 EP claimed
EP-1126833-A2 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES, INC. (US) 2001-08-29 EP claimed
WO-2000045635-A1 THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2000-08-10 WO claimed
WO-2000025768-A1 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES, INC. (US) 2000-05-11 WO claimed
EP-0726903-A1 MATRIX METALLOPROTEASE INHIBITORS SYNTEX INC (US) 1996-08-21 EP claimed
WO-1995012603-A1 MATRIX METALLOPROTEASE INHIBITORS________________________________ SYNTEX (U.S.A.) INC. (US) 1995-05-11 WO claimed
JP-59115893-A None JP disclosed
US-20230371508-A1 COMPOSITIONS AND METHODS FOR KILLING INSECT AND NON-INSECT PESTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2023-11-23 US disclosed
US-11805776-B2 Compositions and methods for killing insect and non-insect pests THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2023-11-07 US disclosed
US-20230348522-A1 METHOD FOR PRODUCING BICYCLIC PHOSPHORAMIDITE DAIICHI SANKYO COMPANY, LIMITED (JP) 2023-11-02 US disclosed
CN-113527680-B Polymer, photosensitive resin composition, pattern forming method, cured film, and electronic component 信越化学工业株式会社 2023-04-28 CN disclosed
EP-3896521-B1 POLYMER, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD, METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT SHINETSU CHEMICAL CO (JP) 2022-12-14 EP disclosed
CN-1134153-A Matrix metalloprotease inhibitors SYNTEX INC (US) 1996-10-23 CN disclosed
US-4981836-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1991-01-01 US disclosed
US-4891297-A STORAGE STABILITY, HIGH COLOR DENSITY FUJI PHOTO FILM CO.,LTD. (JP) 1990-01-02 US disclosed
EP-0323887-A2 Heat-sensitive diazo recording materials FUJI PHOTO FILM CO., LTD. (JP) 1989-07-12 EP disclosed
US-4835133-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-30 US disclosed
JP-S59115893-A HEAT SENSITIVE RECORDING TYPE RELEASE PAPER RICOH CO LTD 1984-07-04 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230371508-A1 COMPOSITIONS AND METHODS FOR KILLING INSECT AND NON-INSECT PESTS BRS3, L3MBTL3, F7 ALDH1A1 2593/4885HSD17B10 1044/4885CFTR 3865/4885
US-11805776-B2 Compositions and methods for killing insect and non-insect pests BRS3, L3MBTL3, F7 ALDH1A1 2593/4885HSD17B10 1044/4885CFTR 3865/4885
US-20230348522-A1 METHOD FOR PRODUCING BICYCLIC PHOSPHORAMIDITE PFAS, ENPP1, NAAA ALDH1A1 2704/4885HSD17B10 4160/4885CFTR 4829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.