Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Dimethyl Phthalate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.59 |
| ▸ | SLC6A3 known ✓ | Q01959 | 4/20 | 0.57 |
| ▸ | SLC6A4 known ✓ | P31645 | 2/20 | 0.55 |
| ▸ | GLA known ✓ | P06280 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | CFTR | P13569 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MYC | P01106 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Phthalate SCHEMBL27342491 | 1.00 | TSHR (0.71) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| Dimethyl Phthalate SCHEMBL28222129 | 0.97 | TSHR (0.68) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| Dimethyl Phthalate SCHEMBL34630 | 0.97 | TSHR (0.74) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| Dimethyl Phthalate SCHEMBL29500970 | 0.97 | TSHR (0.74) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| Dimethyl Phthalate SCHEMBL790124 | 0.97 | TSHR (0.74) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| Dimethyl Phthalate SCHEMBL29669976 | 0.97 | TSHR (0.74) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| Dimethyl Phthalate SCHEMBL30278536 | 0.95 | TSHR (0.71) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| Dimethyl Phthalate SCHEMBL10602130 | 0.95 | TSHR (0.71) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| Dimethyl Phthalate SCHEMBL28376050 | 0.95 | TSHR (0.71) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| Dimethyl Phthalate SCHEMBL27438615 | 0.95 | TSHR (0.71) | TSHRLMNAALDH1A1HSD17B10CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110780368-B | Self-adaptive liquid lens and manufacturing method thereof | 天津大学 | 2021-07-27 | — | — | CN | claimed |
| CN-110780368-A | Self-adaptive liquid lens and manufacturing method thereof | 天津大学 | 2020-02-11 | — | — | CN | claimed |
| CN-108409406-A | A kind of preparation method for lean soil conditioner | 金华市飞凌生物科技有限公司 | 2018-08-17 | — | — | CN | claimed |
| CN-110780368-B | Self-adaptive liquid lens and manufacturing method thereof | 天津大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-110780368-A | Self-adaptive liquid lens and manufacturing method thereof | 天津大学 | 2020-02-11 | — | — | CN | disclosed |
| CN-110418851-A | The treatment of cancer and diagnostic method | GENENTECH INC | 2019-11-05 | — | — | CN | disclosed |
| CN-110150143-A | A kind of breeding method of cherry nursery stock | 浦江县合洪园艺研发有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-110087681-A | The antibody of bind interleukin -2 and its purposes | 佐马美国有限公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-109803680-A | Parathyroid hormone receptor 1(PTH1R) antibodies and uses thereof | 佐马美国有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-109071620-A | TIGIT binding agents and uses thereof | 昂科梅德制药有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-104105711-B | Single-chain antibody and other heteromultimerics | 弗·哈夫曼-拉罗切有限公司 | 2018-11-30 | — | — | CN | disclosed |
| CN-1882568-B | Pyrrol derivatives with antibacterial activity | ASTRAZENECA AB | 2012-03-28 | — | — | CN | disclosed |
| CN-101970460-A | Functional lipid constructs | KODE BIOTECH LTD | 2011-02-09 | — | — | CN | disclosed |
| CN-101506237-A | anti-C5 aR antibodies with improved properties | G2 INFLAMMATION PTY LTD (AU) | 2009-08-12 | — | — | CN | disclosed |
| CN-101218256-A | CD38 antibodies for the treatment of multiple myeloma | GENMAB AS (DK) | 2008-07-09 | — | — | CN | disclosed |
| CN-1882568-A | Pyrrol derivatives with antibacterial activity | ASTRAZENECA AB (SE) | 2006-12-20 | — | — | CN | disclosed |
| CN-1329659-A | Cloth-washing detergent and/or fabric care composition | PROCTER & GAMBLE (US) | 2002-01-02 | — | — | CN | disclosed |
| CN-1329666-A | laundry detergent and/or fabric care compositions | PROCTER & GAMBLE (US) | 2002-01-02 | — | — | CN | disclosed |
| CN-1329658-A | Cloth-washing detergent and/or fabric care composition | PROCTER & GAMBLE (US) | 2002-01-02 | — | — | CN | disclosed |
| CN-1327478-A | Laundry detergent and/or fabric care compositions | PROCTER & GAMBLE (US) | 2001-12-19 | — | — | CN | disclosed |