Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7845680 | 1.00 | ALDH1A1 (0.47) | ALDH1A1TSHRPTGS1DGKALMNA | |
| SCHEMBL28329758 | 1.00 | ALDH1A1 (0.47) | ALDH1A1TSHRPTGS1DGKALMNA | |
| SCHEMBL1539244 | 1.00 | ALDH1A1 (0.47) | ALDH1A1TSHRPTGS1DGKALMNA | |
| SCHEMBL1539265 | 1.00 | ALDH1A1 (0.47) | ALDH1A1TSHRPTGS1DGKALMNA | |
| SCHEMBL28687285 | 1.00 | ALDH1A1 (0.47) | ALDH1A1TSHRPTGS1DGKALMNA | |
| SCHEMBL11514647 | 1.00 | ALDH1A1 (0.47) | ALDH1A1TSHRPTGS1DGKALMNA | |
| SCHEMBL614868 | 0.97 | TSHR (0.50) | ALDH1A1TSHRPTGS1DGKALMNA | |
| SCHEMBL4759428 | 0.92 | TSHR (0.52) | ALDH1A1TSHRPTGS1DGKALMNA | |
| SCHEMBL2235744 | 0.91 | DGKA (0.59) | ALDH1A1TSHRDGKALMNAPAM | |
| SCHEMBL22126637 | 0.91 | DGKA (0.59) | ALDH1A1TSHRDGKALMNAPAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240020529-A1 | PCT/US21/056841 | ISP INVESTMENTS LLC (US) | 2024-01-18 | — | — | US | claimed |
| EP-4236953-A1 | METHOD AND SYSTEM FOR PREDICTING PROPERTIES OF AMORPHOUS SOLID DISPERSIONS USING MACHINE LEARNING | ISP Investments LLC (US) | 2023-09-06 | — | — | EP | claimed |
| CN-116456964-A | Method and system for predicting amorphous solid dispersion characteristics using machine learning | 埃斯普投资有限公司 | 2023-07-18 | — | — | CN | claimed |
| WO-2022093951-A1 | METHOD AND SYSTEM FOR PREDICTING PROPERTIES OF AMORPHOUS SOLID DISPERSIONS USING MACHINE LEARNING | ISP INVESTMENTS LLC (US) | 2022-05-05 | — | — | WO | claimed |
| WO-2022036033-A2 | SOLID STATE FORMS OF AN ORGANIC COMPOUND | SERVIER PHARMACEUTICALS, LLC (US) | 2022-02-17 | — | — | WO | claimed |
| US-20200397756-A1 | A STABLE PHARMACEUTICAL COMPOSITION OF POORLY SOLUBLE NONSTEROIDAL ANTIANDROGENS | KASHIV BIOSCIENCES, LLC | 2020-12-24 | — | — | US | claimed |
| WO-2019155416-A2 | A STABLE PHARMACEUTICAL COMPOSITION OF POORLY SOLUBLE NONSTEROIDAL ANTIANDROGENS | KASHIV PHARMA LLC (US) | 2019-08-15 | — | — | WO | claimed |
| US-11911463-B2 | Topical hyper-allergenic composition and method of treating using the same | ALLEAMIT INC. | 2024-02-27 | — | — | US | disclosed |
| US-20240020529-A1 | PCT/US21/056841 | ISP INVESTMENTS LLC (US) | 2024-01-18 | — | — | US | disclosed |
| US-20230364247-A1 | NON-LINEAR MULTIBLOCK COPOLYMER-DRUG CONJUGATES FOR THE DELIVERY OF ACTIVE AGENTS | THE JOHNS HOPKINS UNIVERSITY | 2023-11-16 | — | — | US | disclosed |
| EP-4236953-A1 | METHOD AND SYSTEM FOR PREDICTING PROPERTIES OF AMORPHOUS SOLID DISPERSIONS USING MACHINE LEARNING | ISP Investments LLC (US) | 2023-09-06 | — | — | EP | disclosed |
| CN-116456964-A | Method and system for predicting amorphous solid dispersion characteristics using machine learning | 埃斯普投资有限公司 | 2023-07-18 | — | — | CN | disclosed |
| US-11660349-B2 | Non-linear multiblock copolymer-drug conjugates for the delivery of active agents | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-05-30 | — | — | US | disclosed |
| WO-2008079404-A2 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF PARKINSON'S DISEASE AND RELATED DISORDERS | COMBINATORX, INCORPORATED (US) | 2008-07-03 | — | — | WO | disclosed |
| US-7297347-B2 | Polyanhydrides | EFRAT BIOPOLYMERS LTD (IL) | 2007-11-20 | — | — | US | disclosed |
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0850049-B1 | COMPOSITION FOR PH-DEPENDENT CONTROLLED RELEASE OF ACTIVE INGREDIENTS AND METHODS FOR PRODUCING IT | POLYMER COREX KUOPIO LTD OY (FI) | 2002-06-26 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |
| US-5656292-A | RELEASE AGENT STARCH SUBSTITUTED WITH ACETATE AND DICARBOXYLATE RESIDUES | ALKO GROUP LTD. (FI) | 1997-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11660349-B2 | Non-linear multiblock copolymer-drug conjugates for the delivery of active agents | VEGFA, UACA, PDE6A | ALDH1A1 1084/4885TSHR 3190/4885PTGS1 241/4885 |
| US-20230364247-A1 | NON-LINEAR MULTIBLOCK COPOLYMER-DRUG CONJUGATES FOR THE DELIVERY OF ACTIVE AGENTS | VEGFA, UACA, PDE6A | ALDH1A1 1084/4885TSHR 3190/4885PTGS1 241/4885 |
| US-20200397756-A1 | A STABLE PHARMACEUTICAL COMPOSITION OF POORLY SOLUBLE NONSTEROIDAL ANTIANDROGENS | AR, SHBG, SULT2A1 | ALDH1A1 260/4885TSHR 4530/4885PTGS1 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.