SCHEMBL3384641

SCHEMBL3384641

COC(=O)C(C)(C)SC(=S)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.49
KCNN4 O15554 1/20 0.44
ELANE P08246 3/20 0.44
TSHR P16473 2/20 0.44
EPHX1 P07099 1/20 0.41
MAPT P10636 1/20 0.41
PRSS1 P07477 1/20 0.40
CTSG P08311 1/20 0.40
CTRB1 P17538 1/20 0.40
CMA1 P23946 1/20 0.40
KMT2A Q03164 2/20 0.39
ALDH1A1 P00352 4/20 0.39
HSD17B10 Q99714 2/20 0.39
LMNA P02545 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALOX12 P18054 1/20 0.39
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
CES1 P23141 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16358214 0.85 TSHR (0.38) SRCELANETSHREPHX1MAPT
SCHEMBL164403 0.83 POLB (0.49) TSHRMAPTKMT2AALDH1A1LMNA
SCHEMBL822806 0.82 EPHX1 (0.42) ELANETSHREPHX1MAPTKMT2A
SCHEMBL13377791 0.81 EPHX1 (0.41) TSHREPHX1MAPTKMT2AALDH1A1
SCHEMBL24244382 0.80 LMNA (0.51) ELANETSHRKMT2AALDH1A1HSD17B10
SCHEMBL822578 0.80 GAA (0.38) ELANETSHREPHX1PRSS1CTSG
SCHEMBL30448922 0.80 POLB (0.38) ELANETSHREPHX1MAPTPRSS1
SCHEMBL3333743 0.79 MAPT (0.44) TSHREPHX1MAPTKMT2AALDH1A1
SCHEMBL16128970 0.78 NPC1 (0.42) ELANETSHRPRSS1CTSGCTRB1
SCHEMBL14124651 0.75 TSHR (0.35) TSHREPHX1PRSS1CTSGCTRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9382346-B2 Gold nanoparticle conjugates and uses thereof COLORADO SCHOOL OF MINES (US) 2016-07-05 US disclosed
US-20160017065-A1 Gold Nanoparticle Conjugates and Uses Thereof COLORADO SCHOOL OF MINES 2016-01-21 US disclosed
US-9175015-B2 Gold nanoparticle conjugates and uses thereof COLORADO SCHOOL OF MINES (US) 2015-11-03 US disclosed
US-20150306256-A1 Lanthanide Nanoparticle Conjugates and Uses Thereof COLORADO STATE UNIVERSITY RESEARCH FOUNDATION 2015-10-29 US disclosed
US-20150258034-A1 GOLD/LANTHANIDE NANOPARTICLE CONJUGATES AND USES THEREOF COLORADO SCHOOL OF MINES 2015-09-17 US disclosed
US-20150250902-A1 pH-RESPONSIVE GADOLINIUM NANOPARTICLE CONJUGATES AND USES THEREOF COLORADO SCHOOL OF MINES (US) 2015-09-10 US disclosed
US-8968705-B2 Gold/lanthanide nanoparticle conjugates and uses thereof COLORADO SCHOOL OF MINES (US) 2015-03-03 US disclosed
US-20120052006-A1 GOLD/LANTHANIDE NANOPARTICLE CONJUGATES AND USES THEREOF COLORADO SCHOOL OF MINES (US) 2012-03-01 US disclosed
US-20100279074-A1 PROCESS FOR PREPARING A POLYMERIC RELIEF STRUCTURE STICHTING DUTCH POLYMER INSTITUTE (NL) 2010-11-04 US disclosed
US-20100279074-A1 PROCESS FOR PREPARING A POLYMERIC RELIEF STRUCTURE STICHTING DUTCH POLYMER INSTITUTE (NL) 2010-11-04 US disclosed
US-20090060840-A1 Lanthanide Nanoparticle Conjugates and Uses Thereof COLORADO STATE UNIVERSITY RESEARCH FOUNDATION 2009-03-05 US disclosed
US-20090060839-A1 Gold Nanoparticle Conjugates and Uses Thereof COLORADO SCHOOL OF MINES 2009-03-05 US disclosed
EP-2019336-A1 Process for preparing a polymeric relief structure Stichting Dutch Polymer Institute (NL) 2009-01-28 EP disclosed
EP-2019336-A1 Process for preparing a polymeric relief structure Stichting Dutch Polymer Institute (NL) 2009-01-28 EP disclosed
WO-2008151915-A1 PROCESS FOR PREPARING A POLYMERIC RELIEF STRUCTURE STICHTING DUTCH POLYMER INSTITUTE (NL) 2008-12-18 WO disclosed
WO-2008151915-A1 PROCESS FOR PREPARING A POLYMERIC RELIEF STRUCTURE STICHTING DUTCH POLYMER INSTITUTE (NL) 2008-12-18 WO disclosed
WO-2008123541-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2008-10-16 WO disclosed
US-20080241737-A1 RESIST COMPOSITION AND PATTERN-FORMING METHOD USING SAME FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080241737-A1 RESIST COMPOSITION AND PATTERN-FORMING METHOD USING SAME FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
EP-1972641-A2 Resist composition and pattern-forming method using same FUJIFILM Corporation (JP) 2008-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150306256-A1 Lanthanide Nanoparticle Conjugates and Uses Thereof SSB, CD47, SLC6A13 SRC 2524/4885KCNN4 2594/4885ELANE 349/4885
US-20090060840-A1 Lanthanide Nanoparticle Conjugates and Uses Thereof SSB, CD47, SLC6A13 SRC 2524/4885KCNN4 2594/4885ELANE 349/4885
US-20120052006-A1 GOLD/LANTHANIDE NANOPARTICLE CONJUGATES AND USES THEREOF SSB, LGALS9, LGALS3 SRC 2476/4885KCNN4 3543/4885ELANE 361/4885
US-20150258034-A1 GOLD/LANTHANIDE NANOPARTICLE CONJUGATES AND USES THEREOF SSB, LGALS9, LGALS3 SRC 2476/4885KCNN4 3543/4885ELANE 361/4885
US-20150250902-A1 pH-RESPONSIVE GADOLINIUM NANOPARTICLE CONJUGATES AND USES THEREOF GOLGA3, GDI1, CA13 SRC 3232/4885KCNN4 1209/4885ELANE 308/4885
US-20160017065-A1 Gold Nanoparticle Conjugates and Uses Thereof CD47, SELP, SELPLG SRC 577/4885KCNN4 4854/4885ELANE 358/4885
US-20090060839-A1 Gold Nanoparticle Conjugates and Uses Thereof CD47, SELP, SELPLG SRC 577/4885KCNN4 4854/4885ELANE 358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.