Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380546 | 0.87 | CYP2C19 (0.42) | ALDH1A1CYP3A4ESR1ESR2TSHR | |
| SCHEMBL3385323 | 0.71 | NAALAD2 (0.41) | ALDH1A1CYP3A4ESR1ESR2TSHR | |
| SCHEMBL3385304 | 0.70 | RIPK1 (0.57) | KMT2AMEN1 | |
| SCHEMBL8458300 | 0.69 | KDM4E (0.41) | ALDH1A1CYP3A4ESR1ESR2BCHE | |
| SCHEMBL3384342 | 0.68 | ALDH1A1 (0.40) | ALDH1A1CYP3A4ESR1ESR2TSHR | |
| SCHEMBL28773067 | 0.66 | ALDH1A1 (0.45) | ALDH1A1CYP3A4ESR1ESR2BCHE | |
| SCHEMBL10623363 | 0.65 | BCHE (0.47) | ALDH1A1CYP3A4BCHETSHRFFAR1 | |
| Adipic Acid SCHEMBL28218965 | 0.65 | CHRM5 (0.59) | ALDH1A1BCHETSHRTBXAS1CYP2C9 | |
| SCHEMBL8459394 | 0.65 | FDPS (0.39) | ALDH1A1CYP3A4ESR1ESR2BCHE | |
| SCHEMBL8460769 | 0.65 | MMP9 (0.39) | ALDH1A1CYP3A4ESR1ESR2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962521-A | PROSTATE GLANDS DISORDERS | GUILFORD PHARMACEUTICALS INC. (US) | 1999-10-05 | — | — | US | claimed |
| EP-1443954-B1 | TARGETED THROMBOSIS BY TISSUE FACTOR POLYPEPTIDES | SCRIPPS RESEARCH INST (US) | 2010-11-24 | — | — | EP | disclosed |
| US-7399743-B2 | Targeted thrombosis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-07-15 | — | — | US | disclosed |
| EP-1443954-A2 | TARGETED THROMBOSIS BY TISSUE FACTOR POLYPEPTIDES | Novartis Pharma GmbH (AT) | 2004-08-11 | — | — | EP | disclosed |
| US-20030194400-A1 | Targeted thrombosis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-10-16 | — | — | US | disclosed |
| WO-2003035688-A2 | TARGETED THROMBOSIS BY TISSUE FACTOR POLYPEPTIDES | NOVARTIS PHARMA GMBH (AT) | 2003-05-01 | — | — | WO | disclosed |
| US-5962521-A | PROSTATE GLANDS DISORDERS | GUILFORD PHARMACEUTICALS INC. (US) | 1999-10-05 | — | — | US | disclosed |