SCHEMBL338536

SCHEMBL338536

C=C(C)C(=O)OCCCCCCCCCCCC[Si](OC)(OC)OC

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.61
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
HTT P42858 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
THRB P10828 1/20 0.44
ALDH1A1 P00352 4/20 0.38
CYP3A4 P08684 1/20 0.33
ACHE P22303 6/20 0.33
LMNA P02545 1/20 0.32
NAAA Q02083 1/20 0.32
RAD52 P43351 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1024774 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL3505241 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL19409836 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL394435 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL19409819 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL1792183 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL4437653 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL9947941 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL1022708 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL339184 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122029219-A Polyester film 三菱化学株式会社 2026-05-12 CN disclosed
CN-122029220-A Polyester film 三菱化学株式会社 2026-05-12 CN disclosed
US-12465559-B2 Fluorescent curable dental composition and cured product thereof KURARAY NORITAKE DENTAL INC. (JP) 2025-11-11 US disclosed
US-20250213434-A1 DENTAL CURABLE COMPOSITION HAVING FAVORABLE COLOR COMPATIBILITY KURARAY NORITAKE DENTAL INC. (JP) 2025-07-03 US disclosed
US-20250206868-A1 METHOD FOR PRODUCING TREATED-SILICA DISPERSED MONOMER COMPOSITION GC CORPORATION (JP) 2025-06-26 US disclosed
WO-2025126917-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2025-06-19 WO disclosed
EP-4545060-A1 COMPOSITION FOR THREE-DIMENSIONAL MODELING AND METHOD FOR PRODUCING DENTAL MODELED OBJECT GC Corporation (JP) 2025-04-30 EP disclosed
WO-2025053161-A1 SURFACE-TREATED ALUMINUM NITRIDE POWDER 株式会社トクヤマ 2025-03-13 WO disclosed
EP-4505992-A1 DENTAL CURABLE COMPOSITION HAVING FAVORABLE COLOR COMPATIBILITY Kuraray Noritake Dental Inc. (JP) 2025-02-12 EP disclosed
US-12220479-B2 Suncare formulation ROHM AND HAAS COMPANY (US) 2025-02-11 US disclosed
EP-2383321-A2 Process for producing an adhesive composition and adhesive tape comprising an adhesive composition produced by said process Nitto Denko Corporation (JP) 2011-11-02 EP disclosed
CN-102083403-A Dental composition and composite resin KURARAY MEDICAL INC 2011-06-01 CN disclosed
US-7951851-B2 Curable composition for dental purposes KURARAY MEDICAL INC. (JP) 2011-05-31 US disclosed
US-20110046261-A1 DENTAL COMPOSITION AND COMPOSITE RESIN KURARAY MEDICAL INC. (JP) 2011-02-24 US disclosed
EP-2275076-A1 DENTAL COMPOSITION AND COMPOSITE RESIN Kuraray Medical Inc. (JP) 2011-01-19 EP disclosed
US-20100210745-A1 Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes REACTIVE SURFACES, LTD. (US) 2010-08-19 US disclosed
US-20100105802-A1 CURABLE COMPOSITION FOR DENTAL PURPOSES KURARAY MEDICAL INC. (JP) 2010-04-29 US disclosed
CN-101600412-A Curable composition for dental use KURARAY MEDICAL INC (JP) 2009-12-09 CN disclosed
EP-2123247-A1 CURABLE COMPOSITION FOR DENTAL PURPOSES Kuraray Medical Inc. (JP) 2009-11-25 EP disclosed
US-20090142593-A1 PRESSURE-SENSITIVE ADHESIVE TAPE NITTO DENKO CORPORATION (JP) 2009-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100105802-A1 CURABLE COMPOSITION FOR DENTAL PURPOSES H1-0, H1-3, H1-2 TSHR 2517/4885POLB 696/4885APEX1 1834/4885
US-12465559-B2 Fluorescent curable dental composition and cured product thereof BRD1, TBCA, BAZ1A TSHR 4128/4885POLB 402/4885APEX1 2291/4885
US-20110046261-A1 DENTAL COMPOSITION AND COMPOSITE RESIN CAD, KATNAL2, ZYX TSHR 3309/4885POLB 623/4885APEX1 4096/4885
US-12220479-B2 Suncare formulation MMS19, TLR7, CD40LG TSHR 3879/4885POLB 1287/4885APEX1 538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.