Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1024774 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3505241 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL19409836 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL394435 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL19409819 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1792183 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL4437653 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL338536 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9947941 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL339184 | 1.00 | TSHR (0.61) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 565 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023136337-A1 | DENTAL COMPOSITION, METHOD FOR MANUFACTURING SAME, AND DENTAL SURFACE-TREATED FILLER | クラレノリタケデンタル株式会社 | 2023-07-20 | — | — | WO | claimed |
| US-20200155421-A1 | TWO-PASTE DENTAL CURABLE COMPOSITION | KURARAY NORITAKE DENTAL INC. (JP) | 2020-05-21 | — | — | US | claimed |
| EP-3646847-A1 | TWO-PASTE TYPE DENTAL CURABLE COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2020-05-06 | — | — | EP | claimed |
| CN-110785159-A | Dual paste type dental curable composition | 可乐丽则武齿科株式会社 | 2020-02-11 | — | — | CN | claimed |
| US-9855196-B2 | Dental curable composition and dental flowable composite resin | KURARAY NORITAKE DENTAL INC. (JP) | 2018-01-02 | — | — | US | claimed |
| US-8895680-B2 | Redox curing-type nonaqueous curable composition | KURARAY NORITAKE DENTAL INC. (JP) | 2014-11-25 | — | — | US | claimed |
| US-7851547-B2 | Curable composition and coated article | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-12-14 | — | — | US | claimed |
| US-20100240798-A1 | REDOX-CURING TYPE NONAQUEOUS CURABLE COMPOSITION | KURARAY MEDICAL INC. (JP) | 2010-09-23 | — | — | US | claimed |
| US-7655722-B2 | Adhesive composition | KURARAY MEDICAL INC. (JP) | 2010-02-02 | — | — | US | claimed |
| EP-1826239-B1 | Curable composition and coated article | SHINETSU CHEMICAL CO (JP) | 2009-08-26 | — | — | EP | claimed |
| JP-1050888-A | — | — | None | — | — | JP | disclosed |
| US-12622847-B2 | Organosilicon compound and dental composition containing same | KURARAY NORITAKE DENTAL INC. (JP) | 2026-05-12 | — | — | US | disclosed |
| EP-3669854-B1 | PHOTOPOLYMERIZABLE DENTAL COMPOSITION | G C DENTAL IND CORP (JP) | 2026-04-08 | — | — | EP | disclosed |
| EP-4717249-A1 | DENTAL COMPOSITION | Shofu Inc. (JP) | 2026-04-01 | — | — | EP | disclosed |
| US-20260083642-A1 | DENTAL COMPOSITION | SHOFU INC (JP) | 2026-03-26 | — | — | US | disclosed |
| US-5192815-A | Ultrafine filler, silane coupling agent, acrylic ester monomer | KURARAY CO., LTD. (JP) | 1993-03-09 | — | — | US | disclosed |
| EP-0368657-A2 | Dental restorative material | KURARAY CO., LTD. (JP) | 1990-05-16 | — | — | EP | disclosed |
| EP-0113367-B1 | METHOD FOR PRODUCING CROSS-LINKED RESIN COATINGS ON SUBSTRATES | BATTELLE DEVELOPMENT CORPORATION (US) | 1989-02-15 | — | — | EP | disclosed |
| EP-0113367-A1 | METHOD FOR PRODUCING CROSS-LINKED RESIN COATINGS ON SUBSTRATES. | BATTELLE DEVELOPMENT CORP (US) | 1984-07-18 | — | — | EP | disclosed |
| WO-1984000375-A1 | METHOD FOR PRODUCING CROSS-LINKED RESIN COATINGS ON SUBSTRATES | BATTELLE DEVELOPMENT CORP (US) | 1984-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240798-A1 | REDOX-CURING TYPE NONAQUEOUS CURABLE COMPOSITION | LPO, CDH1, GPX4 | TSHR 4823/4885POLB 509/4885APEX1 55/4885 |
| US-12622847-B2 | Organosilicon compound and dental composition containing same | MSL1, ITGA1, ITGAL | TSHR 4185/4885POLB 4114/4885APEX1 66/4885 |
| US-20200155421-A1 | TWO-PASTE DENTAL CURABLE COMPOSITION | CAD, DNMT3A, DNMT3B | TSHR 4487/4885POLB 351/4885APEX1 3101/4885 |
| US-20260083642-A1 | DENTAL COMPOSITION | TAS2R42, COL2A1, TAS2R1 | TSHR 1588/4885POLB 1374/4885APEX1 968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.