SCHEMBL339184

SCHEMBL339184

C=C(C)C(=O)OCCCCCCCCCC[Si](OC)(OC)OC

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.61
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
HTT P42858 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
THRB P10828 1/20 0.44
ALDH1A1 P00352 4/20 0.38
CYP3A4 P08684 1/20 0.33
ACHE P22303 6/20 0.33
LMNA P02545 1/20 0.32
NAAA Q02083 1/20 0.32
RAD52 P43351 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1024774 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL3505241 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL19409836 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL394435 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL19409819 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL1792183 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL4437653 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL338536 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL9947941 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL1022708 1.00 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 863 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119899310-A Acrylate polymer, ultraviolet-curable adhesive composition and polarizer 恒美光电股份有限公司 2025-04-29 CN claimed
US-20200155421-A1 TWO-PASTE DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2020-05-21 US claimed
EP-3646847-A1 TWO-PASTE TYPE DENTAL CURABLE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2020-05-06 EP claimed
CN-110785159-A Dual paste type dental curable composition 可乐丽则武齿科株式会社 2020-02-11 CN claimed
US-7655722-B2 Adhesive composition KURARAY MEDICAL INC. (JP) 2010-02-02 US claimed
US-6177534-B1 ADHESIVE BINDER FOR COMPOSITES AND IN SEALANT AND ADHESIVE DENTAL APPLICATIONS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF COMMERCE 2001-01-23 US claimed
US-12624140-B2 Composition containing compound having polyoxyalkylene chain RESONAC CORPORATION (JP) 2026-05-12 US disclosed
US-12624141-B2 Composition set containing compound having polyoxyalkylene chain RESONAC CORPORATION (JP) 2026-05-12 US disclosed
US-20260116040-A1 LAMINATE, OPTICAL MEMBER, AND OPTICAL DEVICE NITTO DENKO CORP (JP) 2026-04-30 US disclosed
EP-4729294-A1 LAMINATE, OPTICAL MEMBER, AND OPTICAL DEVICE Nitto Denko Corporation (JP) 2026-04-22 EP disclosed
EP-3669854-B1 PHOTOPOLYMERIZABLE DENTAL COMPOSITION G C DENTAL IND CORP (JP) 2026-04-08 EP disclosed
EP-4717249-A1 DENTAL COMPOSITION Shofu Inc. (JP) 2026-04-01 EP disclosed
US-20260083642-A1 DENTAL COMPOSITION SHOFU INC (JP) 2026-03-26 US disclosed
EP-1236459-A1 PHOTO-CURABLE REPARATIVE MATERIAL FOR DENTAL USE TOKUYAMA CORPORATION (JP) 2002-09-04 EP disclosed
EP-1226807-A1 DENTAL CURABLE COMPOSITION TOKUYAMA CORPORATION (JP) 2002-07-31 EP disclosed
US-6177534-B1 ADHESIVE BINDER FOR COMPOSITES AND IN SEALANT AND ADHESIVE DENTAL APPLICATIONS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF COMMERCE 2001-01-23 US disclosed
US-5329039-A Bromoalkyl trimethoxy silane, surface treatment of silica filler, improved water resistance of molding resins SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-07-12 US disclosed
EP-0368657-B1 DENTAL RESTORATIVE MATERIAL KURARAY CO., LTD. (JP) 1993-08-04 EP disclosed
US-5192815-A Ultrafine filler, silane coupling agent, acrylic ester monomer KURARAY CO., LTD. (JP) 1993-03-09 US disclosed
EP-0368657-A2 Dental restorative material KURARAY CO., LTD. (JP) 1990-05-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624140-B2 Composition containing compound having polyoxyalkylene chain PIEZO1, HVCN1, TAF11 TSHR 3431/4885POLB 266/4885APEX1 2356/4885
US-20200155421-A1 TWO-PASTE DENTAL CURABLE COMPOSITION CAD, DNMT3A, DNMT3B TSHR 4487/4885POLB 351/4885APEX1 3101/4885
US-20260116040-A1 LAMINATE, OPTICAL MEMBER, AND OPTICAL DEVICE CDH1, ICAM1, ILK TSHR 4581/4885POLB 4395/4885APEX1 3664/4885
US-20260083642-A1 DENTAL COMPOSITION TAS2R42, COL2A1, TAS2R1 TSHR 1588/4885POLB 1374/4885APEX1 968/4885
US-12624141-B2 Composition set containing compound having polyoxyalkylene chain SET, SETD1B, SETDB1 TSHR 3995/4885POLB 22/4885APEX1 644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.