Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.68 |
| ▸ | CNR2 | P34972 | 8/20 | 0.60 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30513088 | 1.00 | CNR1 (0.68) | CNR1CNR2OPRL1KCNH2 | |
| SCHEMBL13191029 | 0.94 | CNR1 (0.61) | CNR1CNR2OPRL1KCNH2 | |
| SCHEMBL10145325 | 0.88 | CNR1 (0.55) | CNR1CNR2 | |
| SCHEMBL24208707 | 0.87 | CNR1 (0.65) | CNR1CNR2OPRL1KCNH2 | |
| SCHEMBL6275234 | 0.87 | CNR1 (0.56) | CNR1CNR2 | |
| SCHEMBL24208913 | 0.85 | CNR1 (0.71) | CNR1CNR2OPRL1KCNH2 | |
| SCHEMBL12064299 | 0.84 | CNR1 (0.64) | CNR1CNR2 | |
| SCHEMBL13934100 | 0.84 | CNR1 (0.60) | CNR1CNR2OPRL1KCNH2 | |
| SCHEMBL907990 | 0.84 | CNR1 (0.53) | CNR1CNR2OPRL1KCNH2 | |
| SCHEMBL25509577 | 0.83 | CNR1 (0.66) | CNR1CNR2OPRL1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655238-B2 | MMPL3 inhibitors, compositions and uses thereof | SHANGHAITECH UNIVERSITY (CN) | 2023-05-23 | — | — | US | disclosed |
| US-11655238-B2 | MMPL3 inhibitors, compositions and uses thereof | SHANGHAITECH UNIVERSITY (CN) | 2023-05-23 | — | — | US | disclosed |
| US-20220017492-A1 | MMPL3 INHIBITORS, COMPOSITIONS AND USES THEREOF | SHANGHAITECH UNIVERSITY (CN) | 2022-01-20 | — | — | US | disclosed |
| US-8088798-B2 | Cannabinoid receptor antagonists/inverse agonists useful for treating obesity | Jensen Discovery, Inc. | 2012-01-03 | — | — | US | disclosed |
| US-8030323-B2 | Pyrazole carboxamide derivatives, pharmaceutical compositions and its preparation | BEIJING MOLECULE SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2011-10-04 | — | — | US | disclosed |
| US-20100160383-A1 | PYRAZOLE CARBOXAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND ITS PREPARATION | BEIJING MOLECULE SCIENCE AND TECHNOLOGY CO., LTD (CN) | 2010-06-24 | — | — | US | disclosed |
| US-20100144791-A1 | CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY (US) | 2010-06-10 | — | — | US | disclosed |
| WO-2010020762-A1 | 1,5-DIARYL-PYRAZOLES AND THEIR USE AS CANNABINOID RECEPTOR NEUTRAL ANTAGONISTS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2010-02-25 | — | — | WO | disclosed |
| WO-2010020762-A1 | 1,5-DIARYL-PYRAZOLES AND THEIR USE AS CANNABINOID RECEPTOR NEUTRAL ANTAGONISTS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2010-02-25 | — | — | WO | disclosed |
| WO-2008056377-A2 | POLYMORPHIC FORMS OF RIMONABANT | CADILA HEALTHCARE LIMITED (IN) | 2008-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655238-B2 | MMPL3 inhibitors, compositions and uses thereof | TIMP3, AFG3L2, MMP3 | CNR1 4650/4885CNR2 4645/4885OPRL1 3496/4885 |
| US-20100144791-A1 | CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING OBESITY | CNR2, CNR1, GPR119 | CNR1 2/4885CNR2 1/4885OPRL1 52/4885 |
| US-20220017492-A1 | MMPL3 INHIBITORS, COMPOSITIONS AND USES THEREOF | TIMP3, AFG3L2, MMP3 | CNR1 4650/4885CNR2 4645/4885OPRL1 3496/4885 |
| US-20100160383-A1 | PYRAZOLE CARBOXAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND ITS PREPARATION | CNR1, CNR2, GPR35 | CNR1 1/4885CNR2 2/4885OPRL1 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.