SCHEMBL3386432

SCHEMBL3386432

[O-][S+](Cc1ccccc1Cl)Cc1ccccc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.50
PNMT P11086 1/20 0.50
TAAR1 Q96RJ0 4/20 0.46
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
PKM P14618 1/20 0.42
LMNA P02545 2/20 0.41
TSHR P16473 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
CHRM2 P08172 1/20 0.41
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
AOC3 Q16853 1/20 0.39
KCNH2 Q12809 1/20 0.39
DPP4 P27487 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5503842 0.82 IDO1 (0.46) IDO1PNMTTAAR1CYP1A2CYP3A4
SCHEMBL29725299 0.82 IDO1 (0.46) IDO1PNMTTAAR1CYP1A2CYP3A4
SCHEMBL22444354 0.77 IDO1 (0.42) IDO1PNMTTAAR1CYP1A2CYP3A4
SCHEMBL13139886 0.76 IDO1 (0.50) IDO1PNMTTAAR1CYP1A2CYP3A4
SCHEMBL22195002 0.73 KMT2A (0.36) PKMLMNATSHRNPC1RAB9A
SCHEMBL644724 0.72
SCHEMBL30123336 0.72
SCHEMBL3240698 0.72 GRIN1 (0.43) IDO1PNMTTAAR1CYP1A2CYP3A4
SCHEMBL15231529 0.71 ALOX15 (0.41) CYP3A4TSHRNPC1RAB9ASLC6A2
SCHEMBL778620 0.71 TAAR1 (0.48) IDO1TAAR1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8367871-B2 Process for production of optically active sulfoxide compound using iron-salan complex catalyst NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-02-05 US disclosed
US-7776582-B2 for gas chromatography; identifying an optically enhanced chiral ionic liquid (OCIL) for enantiomeric resolution SIGMA-ALDRICH CO. (US) 2010-08-17 US disclosed
US-20100094037-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE SULFOXIDE COMPOUND USING IRON-SALAN COMPLEX CATALYST NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-04-15 US disclosed
US-20090145197-A1 Optically Enhanced Chiral Ionic Liquids SIGMA-ALDRICH CO. NEWCO INC. 2009-06-11 US disclosed
US-20060014955-A1 Optically enhanced chiral ionic liquids ADVANCED SEPARATION TECHNOLOGIES INC. (US) 2006-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100094037-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE SULFOXIDE COMPOUND USING IRON-SALAN COMPLEX CATALYST SCLY, SFXN1, SQOR IDO1 358/4885PNMT 2458/4885TAAR1 3202/4885
US-20060014955-A1 Optically enhanced chiral ionic liquids GCG, INF2, ELOVL3 IDO1 737/4885PNMT 2412/4885TAAR1 1789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.