Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.42 |
| ▸ | CTSK | P43235 | 6/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13400277 | 0.86 | EPHX1 (0.38) | CTSKOPRK1OPRD1 | |
| SCHEMBL3387323 | 0.81 | AR (0.33) | CTSK | |
| SCHEMBL3390167 | 0.79 | CTSK (0.37) | MTNR1AMTNR1BCTSKCTSLOPRK1 | |
| SCHEMBL1710752 | 0.78 | BCHE (0.38) | CTSK | |
| SCHEMBL13400239 | 0.74 | HDAC6 (0.38) | MTNR1AMTNR1BCTSKCTSLOPRK1 | |
| SCHEMBL13400259 | 0.74 | HDAC6 (0.38) | MTNR1AMTNR1BCTSKCTSLOPRK1 | |
| SCHEMBL1725728 | 0.74 | EPHX1 (0.39) | CTSKOPRK1OPRD1 | |
| SCHEMBL3386798 | 0.74 | EPHX1 (0.39) | CTSKOPRK1OPRD1ACACB | |
| SCHEMBL1710635 | 0.73 | HTR2A (0.37) | CTSKOPRK1OPRD1 | |
| SCHEMBL1710637 | 0.73 | OPRK1 (0.36) | CTSKCTSLOPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093865-A1 | SULPHUR-LINKED COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA, INC. (US) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093865-A1 | SULPHUR-LINKED COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ALDH1A2, MPST, CLN6 | MTNR1A 109/4885MTNR1B 82/4885CTSK 2722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.