Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1710752 | 0.88 | BCHE (0.38) | CTSKAGTR2 | |
| SCHEMBL3386798 | 0.86 | EPHX1 (0.39) | CTSKOPRK1OPRD1CYP3A4 | |
| SCHEMBL1710885 | 0.82 | BCHE (0.37) | CTSKCTSL | |
| SCHEMBL13459310 | 0.80 | AR (0.36) | CTSKCYP3A4CYP2C19 | |
| SCHEMBL3386807 | 0.79 | MTNR1A (0.42) | CTSKCTSLOPRK1OPRD1MTNR1A | |
| SCHEMBL27996251 | 0.78 | GPR88 (0.46) | MTNR1AMTNR1B | |
| SCHEMBL1724178 | 0.78 | ROCK2 (0.35) | CTSKAGTR2 | |
| SCHEMBL16031201 | 0.77 | GCK (0.36) | RAB9ANPC1AGTR2 | |
| SCHEMBL16031904 | 0.77 | AGTR2 (0.35) | CTSKCTSLAGTR2MTNR1AMTNR1B | |
| SCHEMBL16031844 | 0.76 | HPGD (0.34) | CTSKCTSLCYP3A4HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028088-A2 | SULFUR-LINKED COMPOUNDS FOR TREATING OPTHALMIC DISEASES AND DISORDERS | ACUCELA, INC. (US) | 2010-03-11 | — | — | WO | disclosed |