SCHEMBL3387451

SCHEMBL3387451

O=C(O)c1cc(C(=O)O)c(C(=O)O)cc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.54
CA2 P00918 4/20 0.54
ALDH1A1 P00352 4/20 0.54
CA12 O43570 3/20 0.54
CA7 P43166 3/20 0.54
CA9 Q16790 3/20 0.54
CA14 Q9ULX7 3/20 0.54
PTGS2 P35354 2/20 0.54
ALOX5 P09917 1/20 0.54
TSHR P16473 1/20 0.54
KDM4E B2RXH2 3/20 0.50
PTPN1 P18031 3/20 0.50
CYP3A4 P08684 2/20 0.50
MAPT P10636 2/20 0.50
MEN1 O00255 2/20 0.50
KDR P35968 2/20 0.50
KMT2A Q03164 2/20 0.50
THRB P10828 2/20 0.50
HPGD P15428 2/20 0.50
TNF P01375 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27968302 0.97 CA1 (0.52) CA1CA2ALDH1A1CA12CA7
SCHEMBL27968300 0.97 CA1 (0.52) CA1CA2ALDH1A1CA12CA7
SCHEMBL27968315 0.97 CA1 (0.52) CA1CA2ALDH1A1CA12CA7
SCHEMBL27968301 0.97 CA1 (0.52) CA1CA2ALDH1A1CA12CA7
SCHEMBL163610 0.94 CA1 (0.59) CA1CA2ALDH1A1CA12CA7
SCHEMBL596197 0.91 CA1 (0.56) CA1CA2ALDH1A1CA12CA7
SCHEMBL3427286 0.91 CA1 (0.56) CA1CA2ALDH1A1CA12CA7
SCHEMBL5872953 0.91 CA1 (0.56) CA1CA2ALDH1A1CA12CA7
SCHEMBL22206251 0.91 CA1 (0.56) CA1CA2ALDH1A1CA12CA7
SCHEMBL460201 0.91 CA1 (0.56) CA1CA2ALDH1A1CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117624784-A Flame-retardant high-temperature rope and production process thereof 河间市万洋线缆材料有限公司 2024-03-01 CN claimed
CN-113636841-A Wood ceramic composite material 台州邦博装饰材料有限公司 2021-11-12 CN claimed
CN-103923765-A Detergent Composition For Process Of Manufacturing Semiconductors And Displays COWON INNOTECH INC 2014-07-16 CN claimed
CN-103788070-A DPP-4 inhibitor polymer NANJING HUAWE MEDICAL TECHNOLOGY DEV CO LTD 2014-05-14 CN claimed
US-12528758-B2 Production of aromatic acids and phenolics NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2026-01-20 US disclosed
CN-117624784-A Flame-retardant high-temperature rope and production process thereof 河间市万洋线缆材料有限公司 2024-03-01 CN disclosed
US-20240067593-A1 PRODUCTION OF AROMATIC ACIDS AND PHENOLICS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2024-02-29 US disclosed
EP-4048652-B1 PRODUCTION OF AROMATIC ACIDS AND PHENOLICS TNO (NL) 2023-10-04 EP disclosed
US-20230047816-A1 PFKFB3 INHIBITORS AND THEIR USES GERO PTE. LTD. (SG) 2023-02-16 US disclosed
US-20230047816-A1 PFKFB3 INHIBITORS AND THEIR USES GERO PTE. LTD. (SG) 2023-02-16 US disclosed
WO-2022242322-A1 PHTHALIMIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国药科大学 2022-11-24 WO disclosed
EP-4048652-A1 PRODUCTION OF AROMATIC ACIDS AND PHENOLICS Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO (NL) 2022-08-31 EP disclosed
US-5466553-A Phenolic hydroxyl group-containing polyester binder resin TOMOEGAWA PAPER CO., LTD. (JP) 1995-11-14 US disclosed
EP-0617337-A2 Toner for developing electrostatic image TOMOEGAWA PAPER CO. LTD. (JP) 1994-09-28 EP disclosed
US-5331097-A Improved solubility and fugitivity, dyeing carpet MILLIKEN RESEARCH CORPORATION (US) 1994-07-19 US disclosed
US-5250708-A Polymeric, anionic and fluorescent xanthene dyes; color- and washfastness; nontoxic; red MILLIKEN RESEARCH CORPORATION (US) 1993-10-05 US disclosed
EP-0527648-A2 Poly(oxyalkylene) substituted aminophenol intermediate and xanthene colorant MILLIKEN RESEARCH CORPORATION (US) 1993-02-17 EP disclosed
EP-0527649-A2 Poly(oxyalkylene) substituted xanthene colorant and method for making the same MILLIKEN RESEARCH CORPORATION (US) 1993-02-17 EP disclosed
US-5008449-A Method of synthesis of hydroxy-substituted-4-alkoxyphenylacetic acids THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1991-04-16 US disclosed
WO-1990009976-A1 METHOD OF SYNTHESIS OF HYDROXY-SUBSTITUTED-4-ALKOXYPHENYLACETIC ACIDS THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) 1990-09-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230047816-A1 PFKFB3 INHIBITORS AND THEIR USES PFKFB3, PFKFB4, PFKFB1 CA1 3596/4885CA2 3036/4885ALDH1A1 1943/4885
US-20240067593-A1 PRODUCTION OF AROMATIC ACIDS AND PHENOLICS DDC, PAH, FDPS CA1 1199/4885CA2 526/4885ALDH1A1 66/4885
US-12528758-B2 Production of aromatic acids and phenolics PAH, MCCC2, ACACA CA1 477/4885CA2 345/4885ALDH1A1 18/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.