Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314061 | 0.90 | MEN1 (0.47) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL2166899 | 0.88 | MEN1 (0.54) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL2166822 | 0.83 | PKM (0.49) | MEN1KMT2AHTTCYP1A2BLM | |
| SCHEMBL2165459 | 0.78 | CA12 (0.45) | GAAPTGS2MAPTKDM4EPOLB | |
| SCHEMBL2166342 | 0.77 | TSHR (0.51) | MEN1KMT2ACYP1A2GAAALDH1A1 | |
| SCHEMBL2166768 | 0.75 | MAPT (0.48) | MEN1KMT2ARAB9AHTTHSP90AA1 | |
| SCHEMBL12402403 | 0.73 | ALOX15 (0.44) | HTTCYP1A2ALDH1A1ALOX15 | |
| SCHEMBL2167245 | 0.72 | TPMT (0.44) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL12402513 | 0.72 | CYP2C9 (0.46) | CYP1A2GAAALDH1A1MAPTHPGD | |
| SCHEMBL12402517 | 0.69 | TPMT (0.41) | MEN1KMT2AHTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010034827-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2010-04-01 | — | — | WO | disclosed |