Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314061 | 0.92 | MEN1 (0.47) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL3388283 | 0.88 | MEN1 (0.43) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL2166342 | 0.88 | TSHR (0.51) | MEN1KMT2ACYP1A2ALDH1A1GAA | |
| SCHEMBL12402403 | 0.83 | ALOX15 (0.44) | HTTCYP1A2ALDH1A1ALOX15 | |
| SCHEMBL2166822 | 0.83 | PKM (0.49) | MEN1KMT2AHTTCYP1A2BLM | |
| SCHEMBL12402513 | 0.82 | CYP2C9 (0.46) | CYP1A2ALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL2165459 | 0.82 | CA12 (0.45) | GAAMAPTKDM4EPOLBHDAC6 | |
| SCHEMBL2167245 | 0.80 | TPMT (0.44) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL12402517 | 0.76 | TPMT (0.41) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL28387030 | 0.74 | MEN1 (0.51) | MEN1KMT2ASLC22A6SLC22A8RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350036-B1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2015-04-15 | — | — | EP | claimed |
| US-8563548-B2 | Methylene furanone derivatives and use of said derivatives as a photoprotecting or antioxidant or depigmentation agent in cosmetic or dermatological compositions | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-10-22 | — | — | US | claimed |
| US-20110184059-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2011-07-28 | — | — | US | claimed |
| EP-2350036-B1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2015-04-15 | — | — | EP | disclosed |
| US-8563548-B2 | Methylene furanone derivatives and use of said derivatives as a photoprotecting or antioxidant or depigmentation agent in cosmetic or dermatological compositions | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-10-22 | — | — | US | disclosed |
| US-20110184059-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184059-A1 | METHYLENE FURANONE DERIVATIVES AND USE OF SAID DERIVATIVES AS A PHOTOPROTECTING OR ANTIOXIDANT OR DEPIGMENTATION AGENT IN COSMETIC OR DERMATOLOGICAL COMPOSITIONS | NQO1, ESD, DHPS | MEN1 948/4885KMT2A 1784/4885SLC22A6 4714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.