Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29962749 | 0.87 | AHR (0.48) | ALDH1A1CYP3A4TSHRMAPK1CHRM2 | |
| SCHEMBL597055 | 0.87 | AHR (0.48) | ALDH1A1CYP3A4TSHRMAPK1CHRM2 | |
| Hydrochloric Acid SCHEMBL31475434 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TSHRMAPK1CHRM2 | |
| SCHEMBL2201058 | 0.86 | ALDH1A1 (0.45) | PTGS2PTGS1ALDH1A1CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL31475438 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TSHRMAPK1CHRM2 | |
| Hydrochloric Acid SCHEMBL31475440 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TSHRMAPK1CHRM2 | |
| SCHEMBL3950704 | 0.83 | ALDH1A1 (0.45) | ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL2503083 | 0.83 | ALDH1A1 (0.50) | PTGS2PTGS1ALDH1A1SLC9A1 | |
| SCHEMBL7446405 | 0.83 | PTGS2 (0.44) | PTGS2PTGS1ALDH1A1EPHB4CYP3A4 | |
| SCHEMBL7445894 | 0.80 | PTGS2 (0.42) | PTGS2PTGS1ALDH1A1EPHB4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490342-B1 | DISUBSTITUTED PYRAZOLYL CARBOXANILIDES | BAYER CROPSCIENCE AG (DE) | 2010-12-15 | — | — | EP | disclosed |
| EP-1490342-B1 | DISUBSTITUTED PYRAZOLYL CARBOXANILIDES | BAYER CROPSCIENCE AG (DE) | 2010-12-15 | — | — | EP | disclosed |
| US-7521397-B2 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2009-04-21 | — | — | US | disclosed |
| US-7521397-B2 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2009-04-21 | — | — | US | disclosed |
| US-7521397-B2 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2009-04-21 | — | — | US | disclosed |
| US-7329633-B2 | Disubstituted pyrazolylcarboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-02-12 | — | — | US | disclosed |
| US-7329633-B2 | Disubstituted pyrazolylcarboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-02-12 | — | — | US | disclosed |
| US-7329633-B2 | Disubstituted pyrazolylcarboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-02-12 | — | — | US | disclosed |
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-01-17 | — | — | US | disclosed |
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-01-17 | — | — | US | disclosed |
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-01-17 | — | — | US | disclosed |
| US-20060116414-A1 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-06-01 | — | — | US | disclosed |
| EP-1490342-A1 | DISUBSTITUTED PYRAZOLYL CARBOXANILIDES | Bayer CropScience AG (DE) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003070705-A1 | DISUBSTITUTED PYRAZOLYL CARBOXANILIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116414-A1 | Disubstituted pyrazolyl carboxanilides | MRPL21, RRS1, CBR3 | PTGS2 3485/4885PTGS1 3020/4885ALDH1A1 355/4885 |
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | MRPL21, CBR3, CBR1 | PTGS2 3168/4885PTGS1 2961/4885ALDH1A1 264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.