Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.36 |
| ▸ | FEN1 | P39748 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL597055 | 0.87 | AHR (0.48) | ALDH1A1CYP3A4TSHRMAPK1ABL1 | |
| SCHEMBL29962749 | 0.87 | AHR (0.48) | ALDH1A1CYP3A4TSHRMAPK1ABL1 | |
| SCHEMBL3388331 | 0.86 | PTGS2 (0.46) | ALDH1A1CYP3A4TSHRMAPK1PTGS2 | |
| Hydrochloric Acid SCHEMBL31475438 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TSHRMAPK1ABL1 | |
| Hydrochloric Acid SCHEMBL31475434 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TSHRMAPK1ABL1 | |
| Hydrochloric Acid SCHEMBL31475440 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TSHRMAPK1ABL1 | |
| SCHEMBL2503083 | 0.83 | ALDH1A1 (0.50) | ALDH1A1ABL1PTGS2PTGS1ALOX5AP | |
| SCHEMBL3904951 | 0.80 | FEN1 (0.51) | ALDH1A1TSHRPTGS2PTGS1ALOX5AP | |
| SCHEMBL28413084 | 0.79 | KDM4E (0.47) | ALDH1A1CYP3A4ALOX5APFEN1KMO | |
| SCHEMBL3950704 | 0.79 | ALDH1A1 (0.45) | ALDH1A1CYP3A4TSHRMAPK1AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2640707-B1 | 5-HALOGENOPYRAZOLECARBOXAMIDES | BAYER IP GMBH (DE) | 2017-03-15 | — | — | EP | disclosed |
| US-9375004-B2 | 5-halogenopyrazolecarboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-8580971-B2 | Alkyl-analide producing method | BAYER CROPSCIENCE AG (DE) | 2013-11-12 | — | — | US | disclosed |
| US-8580971-B2 | Alkyl-analide producing method | BAYER CROPSCIENCE AG (DE) | 2013-11-12 | — | — | US | disclosed |
| US-8580971-B2 | Alkyl-analide producing method | BAYER CROPSCIENCE AG (DE) | 2013-11-12 | — | — | US | disclosed |
| US-20130296269-A1 | 5-Halogenopyrazolecarboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-07 | — | — | US | disclosed |
| US-7977363-B2 | Fungicides/bactericides for plant protection; exhibit a strong fortifying effect in plants; for controlling cereal diseases against Puccinia species, and diseases in viticulture and fruit and vegetable production against Botrytis, Venturia or Alternaria species; low toxicity; tolrerance | BAYER CROPSCIENCE AG (DE) | 2011-07-12 | — | — | US | disclosed |
| US-7977363-B2 | Fungicides/bactericides for plant protection; exhibit a strong fortifying effect in plants; for controlling cereal diseases against Puccinia species, and diseases in viticulture and fruit and vegetable production against Botrytis, Venturia or Alternaria species; low toxicity; tolrerance | BAYER CROPSCIENCE AG (DE) | 2011-07-12 | — | — | US | disclosed |
| US-7977363-B2 | Fungicides/bactericides for plant protection; exhibit a strong fortifying effect in plants; for controlling cereal diseases against Puccinia species, and diseases in viticulture and fruit and vegetable production against Botrytis, Venturia or Alternaria species; low toxicity; tolrerance | BAYER CROPSCIENCE AG (DE) | 2011-07-12 | — | — | US | disclosed |
| US-20090118346-A1 | Alkyl-Analide Producing Method | BAYER CROPSCIENCE AG (DE) | 2009-05-07 | — | — | US | disclosed |
| US-20090069398-A1 | Pyrazolyl Carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-03-12 | — | — | US | disclosed |
| US-20080242708-A1 | Biphenyl-Thiazolo-Carboxamides | BAYER CROPSCIENCE AG (DE) | 2008-10-02 | — | — | US | disclosed |
| US-20080242708-A1 | Biphenyl-Thiazolo-Carboxamides | BAYER CROPSCIENCE AG (DE) | 2008-10-02 | — | — | US | disclosed |
| US-20080242708-A1 | Biphenyl-Thiazolo-Carboxamides | BAYER CROPSCIENCE AG (DE) | 2008-10-02 | — | — | US | disclosed |
| EP-1856054-B1 | PYRAZOLYLCARBOXANILIDES | BAYER CROPSCIENCE AG (DE) | 2008-09-17 | — | — | EP | disclosed |
| EP-1856054-B1 | PYRAZOLYLCARBOXANILIDES | BAYER CROPSCIENCE AG (DE) | 2008-09-17 | — | — | EP | disclosed |
| EP-1856054-A1 | PYRAZOLYLCARBOXANILIDES | Bayer CropScience AG (DE) | 2007-11-21 | — | — | EP | disclosed |
| EP-1786794-A2 | BIPHENYL-THIAZOLO-CARBOXAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006092213-A1 | PYRAZOLYLCARBOXANILIDES | BAYER CROPSCIENCE AG (DE) | 2006-09-08 | — | — | WO | disclosed |
| WO-2006024387-A2 | BIPHENYL-THIAZOLO-CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296269-A1 | 5-Halogenopyrazolecarboxamides | CYP3A5, CBR3, HDHD5 | ALDH1A1 3455/4885CYP3A4 20/4885TSHR 2190/4885 |
| US-20090118346-A1 | Alkyl-Analide Producing Method | DCXR, MRPL21, APC | ALDH1A1 106/4885CYP3A4 19/4885TSHR 3122/4885 |
| US-20080242708-A1 | Biphenyl-Thiazolo-Carboxamides | MRPL21, CBR3, NAT1 | ALDH1A1 123/4885CYP3A4 30/4885TSHR 28/4885 |
| US-20090069398-A1 | Pyrazolyl Carboxamides | MRPL21, AADAC, PGLS | ALDH1A1 709/4885CYP3A4 31/4885TSHR 3415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.