SCHEMBL3389230

SCHEMBL3389230

C[Si](C)(C)C[Pt]C1=C(c2cccc3ccccc23)C=CC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.37
MAPT P10636 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
KDM4E B2RXH2 5/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 3/20 0.33
HSD17B10 Q99714 3/20 0.33
ENPP1 P22413 2/20 0.33
NISCH Q9Y2I1 1/20 0.33
ENPP3 O14638 1/20 0.33
GAA P10253 1/20 0.33
TDP1 Q9NUW8 2/20 0.33
TP53 P04637 2/20 0.33
MAPK1 P28482 2/20 0.33
ALOX12 P18054 1/20 0.33
TSHR P16473 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3389222 0.83 ALDH1A1 (0.34) KDM4EALDH1A1HPGDHSD17B10TDP1
SCHEMBL6659957 0.72 NISCH (0.34) ALOX15MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL6660636 0.66 HPRT1 (0.41) MAPTSMN1; SMN2RAB9AALDH1A1HPGD
SCHEMBL12636093 0.61 ALDH1A1 (0.50) ALOX15MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL25302086 0.60 ALDH1A1 (0.59) MAPTSMN1; SMN2KDM4EALDH1A1HPGD
SCHEMBL29350007 0.60 ALDH1A1 (0.59) MAPTSMN1; SMN2KDM4EALDH1A1HPGD
SCHEMBL27953 0.60 ALDH1A1 (0.59) MAPTSMN1; SMN2KDM4EALDH1A1HPGD
SCHEMBL6930009 0.60 HTR7 (0.39) MAPTSMN1; SMN2KDM4EALDH1A1HPGD
SCHEMBL6056141 0.60 HTR7 (0.39) MAPTSMN1; SMN2KDM4EALDH1A1HPGD
SCHEMBL20686423 0.59 MAPT (0.40) ALOX15MAPTSMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12460080-B2 Photocurable silicone compositions and process for manufacture of release liners MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2025-11-04 US disclosed
EP-4107209-A1 PHOTOCURABLE SILICONE COMPOSITIONS AND PROCESS FOR MANUFACTURE OF RELEASE LINERS Momentive Performance Materials Inc. (US) 2022-12-28 EP disclosed
US-20210277243-A1 PHOTOCURABLE SILICONE COMPOSITIONS AND PROCESS FOR MANUFACTURE OF RELEASE LINERS MOMENTIVE PERFORMANCE MATERIALS INC. 2021-09-09 US disclosed
EP-1803728-B1 Silylalkyl platinum (IV) compounds and their production method MOMENTIVE PERFORMANCE MAT INC (US) 2010-12-15 EP disclosed
EP-1050539-B1 Irradiation-curable silicone compositions containing photo-active platinum (IV) compounds GEN ELECTRIC (US) 2007-11-14 EP disclosed
EP-1803728-A1 Silylalkyl platinum (IV) compounds and their production method General Electric Company (US) 2007-07-04 EP disclosed
EP-1050539-A2 Irradiation-curable silicone compositions containing photo-active platinum (IV) compounds GENERAL ELECTRIC COMPANY (US) 2000-11-08 EP disclosed
US-6127446-A CYCLOPENTADIENYLPLATINUM (IV) COMPOUNDS HAVING A TRISUBSTITUTED-SILYL ALIPHATIC GROUP ATTACHED TO PLATINUM BY CARBON-PLATINUM LINKAGES AS HYDROSILYLATION CATALYSTS IN IRRADIATION-CURABLE SILICONES GENERAL ELECTRIC COMPANY (US) 2000-10-03 US disclosed