Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393224 | 0.92 | GBA1 (0.38) | ALDH1A1KDM4ECYP2C9CYP2C19HSD17B10 | |
| SCHEMBL3393250 | 0.92 | MAPK12 (0.40) | ALDH1A1KDM4ECYP2C9CYP2C19KMT2A | |
| SCHEMBL3391110 | 0.91 | GBA1 (0.41) | NPY2RDCTPP1 | |
| SCHEMBL3392562 | 0.90 | KMT2A (0.36) | ALDH1A1KDM4EHSD17B10KMT2AGAA | |
| SCHEMBL3389769 | 0.90 | JAK2 (0.37) | ALDH1A1KDM4ECYP2C9CYP2C19HSD17B10 | |
| SCHEMBL3394251 | 0.90 | PTK2B (0.39) | ALDH1A1KDM4ECYP2C9CYP2C19HSD17B10 | |
| SCHEMBL3422290 | 0.90 | MAPK14 (0.37) | ALDH1A1KDM4ECYP2C9CYP2C19KMT2A | |
| SCHEMBL3392832 | 0.89 | BRAF (0.35) | LMNATP53PTK2BMAPK14 | |
| SCHEMBL3390664 | 0.89 | BRAF (0.35) | ALDH1A1KDM4ETSHRLMNATP53 | |
| SCHEMBL3393248 | 0.89 | MAPT (0.43) | ALDH1A1KDM4EKMT2AGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943243-B1 | KINASE INHIBITORS | LILLY CO ELI (US) | 2010-12-29 | — | — | EP | disclosed |