Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3264376 | 0.85 | CYP1A2 (0.40) | SMN1; SMN2POLBLMNAMEN1KMT2A | |
| SCHEMBL3261819 | 0.83 | KMT2A (0.44) | NPSR1SMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL3260789 | 0.81 | NPSR1 (0.45) | NPSR1SMN1; SMN2KDM4EPOLBAPEX1 | |
| SCHEMBL3385375 | 0.80 | RAB9A (0.45) | NPSR1SMN1; SMN2KDM4EPOLBAPEX1 | |
| SCHEMBL3390240 | 0.79 | PLK1 (0.39) | KDM4EDHODHMAPTALDH1A1HTT | |
| SCHEMBL3261575 | 0.77 | NPC1 (0.52) | NPSR1SMN1; SMN2DHODHBCL2MDM2 | |
| SCHEMBL3264381 | 0.76 | TRPM8 (0.43) | NPSR1SMN1; SMN2KDM4EPOLBAPEX1 | |
| SCHEMBL3263308 | 0.76 | NPSR1 (0.40) | NPSR1SMN1; SMN2KDM4EPOLBAPEX1 | |
| SCHEMBL3262218 | 0.75 | NPSR1 (0.49) | NPSR1SMN1; SMN2KDM4EPOLBAPEX1 | |
| SCHEMBL3393032 | 0.75 | ATM (0.46) | NPSR1SMN1; SMN2KDM4EPOLBBCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |