Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3606088 | 0.92 | POLB (0.48) | KMT2APOLB | |
| SCHEMBL3618576 | 0.82 | ALOX5 (0.53) | KMT2APOLB | |
| SCHEMBL7062037 | 0.76 | HTR2A (0.48) | L3MBTL1 | |
| SCHEMBL8464452 | 0.75 | HTR1A (0.55) | ABCB1 | |
| SCHEMBL19939849 | 0.75 | GPR55 (0.52) | PTPN1POLB | |
| SCHEMBL1972535 | 0.73 | CYP19A1 (0.66) | ABCB1L3MBTL1 | |
| SCHEMBL21568868 | 0.72 | BCHE (0.55) | KMT2AMEN1 | |
| SCHEMBL21574020 | 0.72 | BCHE (0.50) | PTPN1KMT2APOLBMEN1 | |
| SCHEMBL31644032 | 0.72 | MAOB (0.69) | ABCB1KMT2AMEN1 | |
| SCHEMBL18029929 | 0.72 | LTA4H (0.57) | ABCB1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197832-A1 | NOVEL ARYL POTASSIUM CHANNEL BLOCKERS AND USES THEREOF | Bionomics Limited (AU) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009043117-A1 | NOVEL ARYL POTASSIUM CHANNEL BLOCKERS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2009-04-09 | — | — | WO | disclosed |