SCHEMBL339039

SCHEMBL339039

[CH2]C(CC(=O)OCC)OCCO

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.40
MGAM O43451 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
ALDH1A1 P00352 8/20 0.38
TRPA1 O75762 1/20 0.38
ALOX15 P16050 3/20 0.36
TSHR P16473 3/20 0.36
CYP3A4 P08684 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP4F2 P78329 1/20 0.35
CYP4A11 Q02928 1/20 0.35
HSD17B10 Q99714 3/20 0.35
CHRM1 P11229 1/20 0.35
ADORA1 P30542 1/20 0.35
KMT2A Q03164 1/20 0.34
CYP1A2 P05177 1/20 0.33
LMNA P02545 1/20 0.32
CYP2D6 P10635 1/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15518158 0.76 GAA (0.39) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL3066350 0.73
SCHEMBL27735602 0.72 ALDH1A1 (0.37) ALDH1A1TSHRTDP1
SCHEMBL8574175 0.72 MGAM (0.46) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL7914700 0.71
SCHEMBL156111 0.71
SCHEMBL7859418 0.70 GAA (0.48) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL272457 0.70 MGAM (0.48) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL28348752 0.69 MGAM (0.43) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL28374929 0.69 ALDH1A1 (0.36) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3458162-B1 MICRO-PARTICULATE ORGANIC UV ABSORBER COMPOSITION BASF SE (DE) 2024-07-10 EP disclosed
CN-117883308-A Cosmetic or dermatological composition comprising a merocyanine and an oily phase comprising at least one alkyl or alkylene carbonate 莱雅公司 2024-04-16 CN disclosed
EP-4262719-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN OILY PHASE COMPRISING AT LEAST ONE CITRIC ACID ESTER L'OREAL (FR) 2023-10-25 EP disclosed
EP-4262714-A1 COSMETIC COMPOSITION COMPRISING A MEROCYANINE, A TRIAZINE UV-SCREENING AGENT, AND A POLYSACCHARIDE MODIFIED WITH HYDROPHOBIC CHAINS L'OREAL (FR) 2023-10-25 EP disclosed
US-11679069-B2 Cosmetic or dermatological composition comprising a merocyanine and an oily phase comprising at least one alkyl or alkylene carbonate L'OREAL (FR) 2023-06-20 US disclosed
WO-2022129039-A1 COSMETIC COMPOSITION COMPRISING A MEROCYANINE, A TRIAZINE UV-SCREENING AGENT, AND A POLYSACCHARIDE MODIFIED WITH HYDROPHOBIC CHAINS L'OREAL (FR) 2022-06-23 WO disclosed
WO-2022129059-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN OILY PHASE COMPRISING AT LEAST ONE CITRIC ACID ESTER L'OREAL (FR) 2022-06-23 WO disclosed
CN-107260561-B Cosmetic and/or dermatological composition containing merocyanine derivatives 莱雅公司 2022-05-17 CN disclosed
US-20220047483-A1 MICRO-PARTICULATE ORGANIC UV ABSORBER COMPOSITION BASF SE (DE) 2022-02-17 US disclosed
US-20210251868-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN OILY PHASE COMPRISING AT LEAST ONE ALKYL OR ALKYLENE CARBONATE L'OREAL (FR) 2021-08-19 US disclosed
WO-2007071584-A2 USE OF TRANSMISSION DYES FOR PROTECTING HUMAN SKIN FROM BROWNING AND AGEING CIBA HOLDING INC. (CH) 2007-06-28 WO disclosed
US-20060018846-A1 Animo substituted hydroxyphenyl benzophenone derivatives CIBA SPECIALTY CHEMICALS CORP. 2006-01-26 US disclosed
EP-1606270-A2 SYMMETRICAL TRIAZINE DERIVATIVES Ciba SC Holding AG (CH) 2005-12-21 EP disclosed
US-20050255055-A1 Merocyanine derivatives for cosmetic use CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
EP-1569893-A2 AMINO SUBSTITUTED HYDROXYPHENYL BENZOPHENONE DERIVATIVES Ciba SC Holding AG (CH) 2005-09-07 EP disclosed
EP-1549283-A1 MEROCYANINE DERIVATIVES FOR COSMETIC USE Ciba SC Holding AG (CH) 2005-07-06 EP disclosed
WO-2004085412-A2 SYMMETRICAL TRIAZINE DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-10-07 WO disclosed
US-20040191191-A1 Symmetrical triazine derivatives CIBA SPECIALTY CHEMICALS CORP. 2004-09-30 US disclosed
WO-2004052837-A2 AMINO SUBSTITUTED HYDROXYPHENYL BENZOPHENONE DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-06-24 WO disclosed
WO-2004006878-A1 MEROCYANINE DERIVATIVES FOR COSMETIC USE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11679069-B2 Cosmetic or dermatological composition comprising a merocyanine and an oily phase comprising at least one alkyl or alkylene carbonate KRT18, DSG1, CUTA GAA 1631/4885MGAM 2651/4885SI 3093/4885
US-20210251868-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN OILY PHASE COMPRISING AT LEAST ONE ALKYL OR ALKYLENE CARBONATE KRT18, DSC1, DSG1 GAA 1864/4885MGAM 2840/4885SI 3270/4885
US-20220047483-A1 MICRO-PARTICULATE ORGANIC UV ABSORBER COMPOSITION MCM4, UGT1A4, CCNB1 GAA 2584/4885MGAM 2429/4885SI 1297/4885
US-20040191191-A1 Symmetrical triazine derivatives H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, RNF168, CYC1 GAA 4478/4885MGAM 4599/4885SI 3776/4885
US-20060018846-A1 Animo substituted hydroxyphenyl benzophenone derivatives C5, C9, C1S GAA 4775/4885MGAM 4873/4885SI 3685/4885
US-20050255055-A1 Merocyanine derivatives for cosmetic use C5, MSH6, C1R GAA 4544/4885MGAM 4723/4885SI 3899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.