Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3390616 | 0.89 | RAB9A (0.31) | ALDH1A1RAB9AGAA | |
| SCHEMBL3393400 | 0.75 | ALDH1A1 (0.44) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL3391681 | 0.71 | ALDH1A1 (0.36) | ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL14338091 | 0.69 | ALDH1A1 (0.47) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL6690666 | 0.69 | ALDH1A1 (0.42) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL390919 | 0.66 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2A | |
| SCHEMBL3389367 | 0.65 | ALDH1A1 (0.45) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL3393407 | 0.64 | KDM4E (0.40) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL13712963 | 0.64 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL3392351 | 0.64 | MAPT (0.46) | ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560827-B1 | ANTI-INFECTIVE AGENTS | ABBOTT LAB (US) | 2010-12-29 | — | — | EP | disclosed |
| US-20050075331-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2005-04-07 | — | — | US | disclosed |
| US-20040167123-A1 | Anti-infective agents | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162285-A1 | Anti-infective agents | POLR1C, RPL5, POLB | ALDH1A1 1434/4885RAB9A 2572/4885GAA 172/4885 |
| US-20040167123-A1 | Anti-infective agents | SERPINB1, CYP51A1, ZC3HAV1 | ALDH1A1 891/4885RAB9A 2546/4885GAA 494/4885 |
| US-20050075331-A1 | Anti-infective agents | RPL35, POLI, POLRMT | ALDH1A1 1592/4885RAB9A 2459/4885GAA 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.