SCHEMBL339121

SCHEMBL339121

Nc1cccc(-c2ccc(Br)cc2)c1[N+](=O)[O-]

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLK4 O00444 1/20 0.39
AURKA O14965 1/20 0.39
JAK2 O60674 1/20 0.39
LCK P06239 1/20 0.39
CDK1 P06493 1/20 0.39
CSF1R P07333 1/20 0.39
LYN P07948 1/20 0.39
FGFR1 P11362 1/20 0.39
SRC P12931 1/20 0.39
PRKACA P17612 1/20 0.39
RPS6KB1 P23443 1/20 0.39
CDK2 P24941 1/20 0.39
MARK3 P27448 1/20 0.39
AKT1 P31749 1/20 0.39
AKT2 P31751 1/20 0.39
KDR P35968 1/20 0.39
BLK P51451 1/20 0.39
CSNK2A1 P68400 1/20 0.39
ROCK1 Q13464 1/20 0.39
MARK2 Q7KZI7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1556277 0.84 ALDH1A1 (0.53) PRKACAALDH1A1MAPTTDP1MEN1
SCHEMBL28185634 0.83 ALDH1A1 (0.37) PRKACAALDH1A1MAPTTDP1MEN1
SCHEMBL28184976 0.83 PTGS2 (0.44) LCKCSF1RFGFR1PRKACAKDR
SCHEMBL28185643 0.82 LOXL2 (0.49) AKT2ALDH1A1MAPTTDP1MEN1
SCHEMBL28185641 0.80 APP (0.47) CDK2ALDH1A1MAPTXDHNPC1
SCHEMBL28184960 0.76 BRD4 (0.41) ALDH1A1TDP1MEN1KMT2APOLB
SCHEMBL5838057 0.76 MAPT (0.50) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL11551067 0.75 TDP1 (0.52) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL3390153 0.75 TDP1 (0.52) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL2547152 0.75 ALDH1A1 (0.41) ALDH1A1MAPTTDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1602648-B2 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO (JP) 2025-03-26 EP disclosed
CN-106450039-B Organic light emitting device 三星显示有限公司 2020-03-06 CN disclosed
CN-102471269-B Nitrogen-containing heterocyclic derivative and organic electroluminescent element containing same IDEMITSU KOSAN CO.,LTD. (JP) 2016-02-03 CN disclosed
CN-101503393-B Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same IDEMITSU KOSAN CO.,LTD. (JP) 2015-08-19 CN disclosed
US-20130306955-A1 NITROGENATED HETEROCYCLIC DERIVATIVE, ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-11-21 US disclosed
EP-1602648-B1 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO (JP) 2013-04-17 EP disclosed
CN-101812021-B Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same IDEMITSU KOSAN CO 2012-12-26 CN disclosed
CN-102471269-A Nitrogen-containing heterocyclic derivative and organic electroluminescent element containing same IDEMITSU KOSAN CO 2012-05-23 CN disclosed
CN-1784388-B Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same IDEMITSU KOSAN CO.,LTD. (JP) 2012-02-22 CN disclosed
US-8097349-B2 Nitrogen containing heterocycle derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-01-17 US disclosed
US-7851071-B2 2-[4-(10-naphthalene-2-yl-anthracene-9-yl)-phenyl]-1-phenyl-1H-benzimidazole; elevation of luminance and of efficiency in light emission even under low driving voltage IDEMITSU KOSAN CO., LTD. (JP) 2010-12-14 US disclosed
CN-101812021-A Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same IDEMITSU KOSAN CO 2010-08-25 CN disclosed
US-20100193773-A1 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD, (JP) 2010-08-05 US disclosed
EP-2174932-A2 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same Idemitsu Kosan Co., Ltd. (JP) 2010-04-14 EP disclosed
EP-2174933-A2 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same Idemitsu Kosan Co., Ltd. (JP) 2010-04-14 EP disclosed
CN-101503393-A Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same IDEMITSU KOSAN CO (JP) 2009-08-12 CN disclosed
US-20060147747-A1 2-[4-(10-naphthalene-2-yl-anthracene-9-yl)-phenyl]-1-phenyl-1H-benzimidazole; elevation of luminance and of efficiency in light emission even under low driving voltage IDEMITSU KOSAN CO., LTD. (JP) 2006-07-06 US disclosed
CN-1784388-A Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same IDEMITSU KOSAN CO (JP) 2006-06-07 CN disclosed
EP-1602648-A1 NITROGEN-CONTAINING HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2005-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100193773-A1 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same NSD1, EED, ERG PLK4 1781/4885AURKA 931/4885JAK2 1233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.