Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28853110 | 0.86 | LOXL2 (0.41) | LOXL2TAAR1TDP1ALDH1A1MEN1 | |
| SCHEMBL28184960 | 0.84 | BRD4 (0.41) | TDP1ALDH1A1MEN1POLBKMT2A | |
| SCHEMBL1556277 | 0.83 | ALDH1A1 (0.53) | CA9CA12CA1CA2CA4 | |
| SCHEMBL28185634 | 0.82 | ALDH1A1 (0.37) | TDP1ALDH1A1MEN1POLBMAPT | |
| SCHEMBL28184976 | 0.82 | PTGS2 (0.44) | TDP1ALDH1A1MEN1POLBMAPT | |
| SCHEMBL339121 | 0.82 | PLK4 (0.39) | CA9CA12CA2TDP1ALDH1A1 | |
| SCHEMBL28185597 | 0.79 | PTGES (0.38) | ALDH1A1POLBMAPTHPRT1 | |
| SCHEMBL28185641 | 0.78 | APP (0.47) | ALDH1A1MAPTRAB9A | |
| SCHEMBL5838057 | 0.78 | MAPT (0.50) | CA9CA12CA1CA2TDP1 | |
| SCHEMBL28184961 | 0.77 | DPP4 (0.43) | LOXL2TDP1ALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104011010-B | Bisaniline compounds and its manufacture method | 组合化学工业株式会社 | 2017-11-28 | — | — | CN | disclosed |