Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18438030 | 0.85 | RAB9A (0.49) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL31006744 | 0.84 | APP (0.49) | APPHTR7MAPTNPC1RAB9A | |
| SCHEMBL5838057 | 0.84 | MAPT (0.50) | MAPTSMN1; SMN2TSHRHPGDALDH1A1 | |
| SCHEMBL28233631 | 0.83 | HTR7 (0.52) | APPHTR7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13983293 | 0.82 | APP (0.47) | APPHTR7MAPTABL1ABCB1 | |
| SCHEMBL28184960 | 0.81 | BRD4 (0.41) | RAB9AHDAC8ALDH1A1 | |
| SCHEMBL1556277 | 0.80 | ALDH1A1 (0.53) | MAPTNPC1RAB9ASMN1; SMN2HDAC2 | |
| SCHEMBL28184979 | 0.80 | KMT2A (0.49) | MAPTSMN1; SMN2TSHRHPGDALDH1A1 | |
| SCHEMBL339121 | 0.80 | PLK4 (0.39) | MAPTNPC1RAB9ACDK2ALDH1A1 | |
| SCHEMBL28184976 | 0.80 | PTGS2 (0.44) | MAPTABL1ALDH1A1NFE2L2MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104011010-B | Bisaniline compounds and its manufacture method | 组合化学工业株式会社 | 2017-11-28 | — | — | CN | disclosed |