Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389359 | 1.00 | ALOX5 (0.36) | ALOX5LMNAPGRCYP3A4CYP2D6 | |
| SCHEMBL3390127 | 1.00 | ALOX5 (0.36) | ALOX5LMNAPGRCYP3A4CYP2D6 | |
| SCHEMBL3388102 | 1.00 | ALOX5 (0.36) | ALOX5LMNAPGRCYP3A4CYP2D6 | |
| SCHEMBL3390606 | 1.00 | ALOX5 (0.36) | ALOX5LMNAPGRCYP3A4CYP2D6 | |
| SCHEMBL3390843 | 1.00 | ALOX5 (0.36) | ALOX5LMNAPGRCYP3A4CYP2D6 | |
| SCHEMBL7911738 | 0.82 | PTGER2 (0.31) | — | |
| SCHEMBL13909313 | 0.81 | CYP19A1 (0.36) | ALOX5 | |
| SCHEMBL27721319 | 0.69 | — | — | |
| SCHEMBL27721303 | 0.69 | — | — | |
| SCHEMBL27721326 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368013-B1 | CYCLOHEXENONE DERIVATIVE FOR TREATING DIABETIC NEUROPATHY | MEIJI DAIRIES CORP (JP) | 2010-12-22 | — | — | EP | disclosed |
| US-7838565-B2 | Use of cyclohexenone derivatives in the manufacture of a medicament for treating diabetic complications | MEIJI DAIRIES CORPORATION (JP) | 2010-11-23 | — | — | US | disclosed |
| EP-1322748-B1 | STEM CELL DIFFERENTIATION-INDUCING PROMOTER | MEIJI DAIRIES CORP (JP) | 2009-12-02 | — | — | EP | disclosed |
| EP-1368014-B1 | USE OF CYCLOHEXENONE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT IN THE TREATMENT OF DYSURIA | MEIJI DAIRIES CORP (JP) | 2006-11-22 | — | — | EP | disclosed |
| US-6906107-B2 | Use of cyclohexenone derivatives for the manufacture of a medicament in the treatment of dysuria | MEIJI DAIRIES CORPORATION (JP) | 2005-06-14 | — | — | US | disclosed |
| US-20040132829-A1 | Use of cyclohexenone derivatives for the manufacture of a medicament in the treatment of dysuria | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2004-07-08 | — | — | US | disclosed |
| US-20040115810-A1 | Stem cell differentiation-inducing promoter | MEIJI DAIRIES CORPORATION (JP) | 2004-06-17 | — | — | US | disclosed |
| US-20040102527-A1 | Use of cyclohexenone derivatives in the manufacture of a medicament for treating diabetic complications | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2004-05-27 | — | — | US | disclosed |
| EP-1368013-A1 | USE OF A CYCLOHEXENONE DERIVATIVES IN THE MANUFACTURE OF A MEDICAMENT FOR TREATING DIABETIC COMPLICATIONS | Meiji Dairies Corporation (JP) | 2003-12-10 | — | — | EP | disclosed |
| EP-1368014-A1 | USE OF CYCLOHEXENONE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT IN THE TREATMENT OF DYSURIA | Meiji Dairies Corporation (JP) | 2003-12-10 | — | — | EP | disclosed |
| EP-1322748-A2 | STEM CELL DIFFERENTIATION-INDUCING PROMOTER | Meiji Dairies Corporation (JP) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002066023-A1 | USE OF A CYCLOHEXENONE DERIVATIVES IN THE MANUFACTURE OF A MEDICAMENT FOR TREATING DIABETIC COMPLICATIONS | MEIJI DAIRIES CORPORATION (JP) | 2002-08-29 | — | — | WO | disclosed |
| WO-2002066024-A1 | USE OF CYCLOHEXENONE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT IN THE TREATMENT OF DYSURIA | MEIJI DAIRIES CORPORATION (JP) | 2002-08-29 | — | — | WO | disclosed |
| WO-2002029014-A2 | STEM CELL DIFFERENTIATION-INDUCING PROMOTER | MEIJI DAIRIES CORPORATION (JP) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132829-A1 | Use of cyclohexenone derivatives for the manufacture of a medicament in the treatment of dysuria | ADH1A, ADH1C, NDUFB7 | ALOX5 852/4885LMNA 1761/4885PGR 4228/4885 |
| US-20040102527-A1 | Use of cyclohexenone derivatives in the manufacture of a medicament for treating diabetic complications | GPR119, CYC1, CYP11B1 | ALOX5 155/4885LMNA 2236/4885PGR 3854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.