Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | TDO2 | P48775 | 1/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21831232 | 0.83 | IDO1 (0.38) | IDO1TDO2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL14603365 | 0.78 | IDO1 (0.53) | IDO1TDO2OPRL1OPRM1OPRD1 | |
| SCHEMBL67123 | 0.76 | CES2 (0.50) | CES2CES1TRPA1MAPK1DPP4 | |
| SCHEMBL7520144 | 0.74 | IDO1 (0.52) | IDO1TDO2OPRL1OPRM1OPRD1 | |
| SCHEMBL7522383 | 0.74 | IDO1 (0.50) | IDO1TDO2OPRL1OPRM1OPRD1 | |
| SCHEMBL11089004 | 0.74 | CES2 (0.37) | IDO1TDO2CES2CES1TRPA1 | |
| SCHEMBL1641150 | 0.74 | ACP3 (0.48) | OPRL1OPRM1OPRD1OPRK1CES2 | |
| SCHEMBL29975957 | 0.74 | IDO1 (0.52) | IDO1TDO2OPRL1OPRM1OPRD1 | |
| SCHEMBL477560 | 0.74 | IDO1 (0.50) | IDO1TDO2OPRL1OPRM1OPRD1 | |
| SCHEMBL8319597 | 0.74 | IDO1 (0.50) | IDO1TDO2OPRL1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024230246-A1 | POLYPEPTIDE RADIONUCLIDE COMPLEX TARGETING FIBROBLAST ACTIVATION PROTEIN AND USE THEREOF | 成都纽瑞特医疗科技股份有限公司 | 2024-11-14 | — | — | WO | claimed |
| CN-104716352-A | Use of crosslinking type polybenzimidazole porous separating membrane in liquid flow battery | DALIAN CHEMICAL PHYSICS INST | 2015-06-17 | — | — | CN | claimed |
| WO-2024230246-A1 | POLYPEPTIDE RADIONUCLIDE COMPLEX TARGETING FIBROBLAST ACTIVATION PROTEIN AND USE THEREOF | 成都纽瑞特医疗科技股份有限公司 | 2024-11-14 | — | — | WO | disclosed |
| CN-113754597-B | Benzhydryl piperazine compound containing linear olefin and preparation method thereof | 凯美克(上海)医药科技有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-113754597-B | Benzhydryl piperazine compound containing linear olefin and preparation method thereof | 凯美克(上海)医药科技有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-109803992-B | Isocyanate composition and method for producing isocyanate polymer | 旭化成株式会社 | 2022-05-24 | — | — | CN | disclosed |
| CN-109843963-B | Isocyanate composition, method for producing isocyanate polymer, and isocyanate polymer | 旭化成株式会社 | 2022-05-13 | — | — | CN | disclosed |
| CN-113754597-A | Benzhydrylpiperazine compound containing linear chain olefin and preparation method thereof | 凯美克(上海)医药科技有限公司 | 2021-12-07 | — | — | CN | disclosed |
| CN-113754597-A | Benzhydrylpiperazine compound containing linear chain olefin and preparation method thereof | 凯美克(上海)医药科技有限公司 | 2021-12-07 | — | — | CN | disclosed |
| CN-113754666-A | Benzopyrazine compound and synthesis method thereof | 凯美克(上海)医药科技有限公司 | 2021-12-07 | — | — | CN | disclosed |
| CN-104716352-A | Use of crosslinking type polybenzimidazole porous separating membrane in liquid flow battery | DALIAN CHEMICAL PHYSICS INST | 2015-06-17 | — | — | CN | disclosed |
| EP-1711617-A1 | METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTICS COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005064008-A9 | METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTIC COMPOUNDS | GILEAD SCIENCES INC (US) | 2006-09-28 | — | — | WO | disclosed |
| EP-1673336-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | Merck Frosst Canada Ltd. (CA) | 2006-06-28 | — | — | EP | disclosed |
| US-20050239054-A1 | Method and compositions for identifying anti-HIV therapeutic compounds | GILEAD SCIENCES. INC. | 2005-10-27 | — | — | US | disclosed |
| US-20050209197-A1 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | GILEAD SCIENCES, INC. | 2005-09-22 | — | — | US | disclosed |
| WO-2005064008-A1 | METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2005-07-14 | — | — | WO | disclosed |
| WO-2005019161-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2005-03-03 | — | — | WO | disclosed |
| EP-1509537-A2 | CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH | GILEAD SCIENCES, INC. (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003090690-A2 | CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH | GILEAD SCIENCES, INC. (US) | 2003-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209197-A1 | Cellular accumulation of phosphonate analogs of HIV protease inhibitor compounds | PPA1, PPME1, PNP | IDO1 2602/4885TDO2 4250/4885OPRL1 4463/4885 |
| US-20050239054-A1 | Method and compositions for identifying anti-HIV therapeutic compounds | CES1, PNP, PGLS | IDO1 3997/4885TDO2 4089/4885OPRL1 4133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.