Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16632702 | 0.76 | SLC6A2 (0.41) | ALDH1A1CYP2C9CYP2C19DPP4IDO1 | |
| SCHEMBL16632474 | 0.76 | SLC6A2 (0.41) | ALDH1A1CYP2C9CYP2C19DPP4IDO1 | |
| SCHEMBL3871873 | 0.75 | ALDH1A1 (0.36) | ALDH1A1CYP1A2CYP2C9CYP2C19IDO1 | |
| SCHEMBL3392138 | 0.74 | IDO1 (0.52) | CES2CES1TRPA1ALDH1A1CYP1A2 | |
| SCHEMBL67123 | 0.74 | CES2 (0.50) | CES2CES1TRPA1DPP4F2 | |
| SCHEMBL29161116 | 0.73 | ALDH1A1 (0.34) | ALDH1A1CYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL11601054 | 0.73 | ADRA2C (0.45) | ALDH1A1CYP2C9CYP2C19TSHRCYP2D6 | |
| SCHEMBL13714106 | 0.73 | MEN1 (0.48) | CYP2C9TSHRCYP2D6CYP3A4SLC6A2 | |
| SCHEMBL1641150 | 0.73 | ACP3 (0.48) | CES2CES1TRPA1ALDH1A1CYP2C9 | |
| SCHEMBL7520144 | 0.73 | IDO1 (0.52) | CES2CES1TRPA1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3864020-A1 | MACROCYCLIC FLU ENDONUCLEASE INHIBITORS | Janssen BioPharma, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |
| US-4442202-A | SILVER HALIDE, REDOX SYSTEM, ORGANOBROMINE COMPOUND, STORAGE STABILITY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1984-04-10 | — | — | US | disclosed |
| US-4396712-A | ORGANIC SILVER SALT OXIDIZER, REDUCING AGENT, SILVER HALIDE OR SILVER HALIDE FORMER, TONER, BINDER, HYDROXYPHENYLBENZOTRIAZOLE | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1983-08-02 | — | — | US | disclosed |
| US-4332889-A | IMPROVED SENSITIVITY, STORAGE STABILITY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1982-06-01 | — | — | US | disclosed |