Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 6/20 | 0.38 |
| ▸ | HTR6 | P50406 | 6/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | HTR7 | P34969 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392207 | 0.76 | PRMT1 (0.62) | PRMT1RXFP1MAPTALDH1A1PKM | |
| SCHEMBL13680868 | 0.73 | PRMT1 (0.49) | PRMT1RXFP1MAPTALDH1A1PKM | |
| SCHEMBL22042121 | 0.70 | PRMT1 (0.54) | PRMT1MAPTALDH1A1PKMHPGD | |
| SCHEMBL3392203 | 0.70 | SCN8A (0.40) | SCN8AHTR2ACHEK1CA12CA1 | |
| SCHEMBL8348550 | 0.69 | SCN8A (0.55) | MAPTALDH1A1TSHRSCN8ALMNA | |
| SCHEMBL4575327 | 0.68 | BCHE (0.59) | SCN8AL3MBTL1CA1CA2 | |
| Hydrochloric Acid SCHEMBL6122751 | 0.68 | SCN8A (0.54) | MAPTALDH1A1TSHRSCN8ALMNA | |
| SCHEMBL4150750 | 0.68 | KIF11 (0.49) | MAPTALDH1A1SCN8ASCN10ACA12 | |
| SCHEMBL19243611 | 0.67 | SCN8A (0.55) | MAPTALDH1A1TSHRSCN8ASMN1; SMN2 | |
| SCHEMBL9903315 | 0.67 | SCN8A (0.58) | MAPTSCN8ASMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246329-A1 | 4(1H)-pyridinone derivatives and their use as antimalaria agents | Glaxo Group Limited (GB) | 2010-11-03 | — | — | EP | disclosed |