Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 6/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393341 | 0.81 | KCNH2 (0.43) | METAP2METAP1GRM5KCNH2FFAR1 | |
| SCHEMBL3392275 | 0.80 | KCNH2 (0.46) | METAP2METAP1GRM5KCNH2FFAR1 | |
| SCHEMBL3395596 | 0.79 | KCNH2 (0.40) | L3MBTL1METAP2METAP1GRM5KCNH2 | |
| SCHEMBL3393481 | 0.73 | MAPT (0.38) | L3MBTL1CYP11B2KDM4EHSD17B10TSHR | |
| SCHEMBL3392062 | 0.72 | KCNH2 (0.54) | METAP2METAP1GRM5KCNH2FFAR1 | |
| SCHEMBL3397454 | 0.72 | OXTR (0.31) | — | |
| SCHEMBL3393142 | 0.67 | CYP19A1 (0.41) | KCNH2CYP11B2HSD17B10ALDH1A1 | |
| SCHEMBL13425594 | 0.66 | KCNH2 (0.38) | METAP2METAP1KCNH2FFAR1TGFBR1 | |
| SCHEMBL3393337 | 0.66 | KCNH2 (0.58) | GRM5KCNH2TGFBR1HSD17B10ALDH1A1 | |
| SCHEMBL3397575 | 0.66 | KCNH2 (0.43) | KCNH2TGFBR1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |