Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | GRK6 | P43250 | 3/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3395055 | 0.90 | AKR1C2 (0.43) | KDM4EPOLBKMT2AAKR1C2HSD17B10 | |
| SCHEMBL3392351 | 0.87 | MAPT (0.46) | KDM4EPOLBCA12CA1CA2 | |
| SCHEMBL3391447 | 0.82 | MAOB (0.44) | KDM4EKMT2AHSD17B10 | |
| SCHEMBL3395051 | 0.80 | ALDH1A1 (0.44) | KDM4EPOLBCA12CA1CA2 | |
| SCHEMBL1523640 | 0.77 | AKR1C3 (0.48) | KDM4EPOLBCA12CA1CA2 | |
| SCHEMBL3395053 | 0.76 | ALDH1A1 (0.48) | CA12CA1CA2CA4CA7 | |
| SCHEMBL5097715 | 0.73 | KMT2A (0.42) | KDM4EPOLBCA12CA1CA2 | |
| SCHEMBL3391436 | 0.70 | MEN1 (0.49) | KDM4EKMT2AHSD17B10 | |
| SCHEMBL14095561 | 0.69 | ALDH1A1 (0.46) | KDM4EMAPTKMT2ALMNA | |
| SCHEMBL335046 | 0.68 | ALDH1A1 (0.45) | KDM4EMAPTKMT2AABCC8KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560827-B1 | ANTI-INFECTIVE AGENTS | ABBOTT LAB (US) | 2010-12-29 | — | — | EP | disclosed |
| US-20050075331-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2005-04-07 | — | — | US | disclosed |
| US-20040167123-A1 | Anti-infective agents | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
| US-20040087577-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162285-A1 | Anti-infective agents | POLR1C, RPL5, POLB | KDM4E 4352/4885POLB 3/4885CA12 4101/4885 |
| US-20040167123-A1 | Anti-infective agents | SERPINB1, CYP51A1, ZC3HAV1 | KDM4E 4075/4885POLB 35/4885CA12 4557/4885 |
| US-20050075331-A1 | Anti-infective agents | RPL35, POLI, POLRMT | KDM4E 3897/4885POLB 19/4885CA12 4493/4885 |
| US-20040087577-A1 | Anti-infective agents | POLR1C, RPL5, POLB | KDM4E 4352/4885POLB 3/4885CA12 4101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.