Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | GRK6 | P43250 | 3/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392363 | 0.90 | KDM4E (0.43) | AKR1C2HSD17B10PTGS1AKR1C3KDM4E | |
| SCHEMBL3395051 | 0.87 | ALDH1A1 (0.44) | AKR1C2HSD17B10PTGS1AKR1C3KDM4E | |
| SCHEMBL3392351 | 0.80 | MAPT (0.46) | AKR1C2HSD17B10PTGS1AKR1C3KDM4E | |
| SCHEMBL1523744 | 0.77 | AKR1C3 (0.48) | AKR1C2HSD17B10PTGS1AKR1C3KDM4E | |
| SCHEMBL3395053 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL3389375 | 0.73 | CA2 (0.40) | GRK6LCKALDH1A1HPGDCYP2C9 | |
| SCHEMBL3391447 | 0.72 | MAOB (0.44) | HSD17B10KDM4EALDH1A1MEN1HPGD | |
| SCHEMBL5627690 | 0.70 | KMT2A (0.43) | KDM4EALDH1A1POLBMMP2MEN1 | |
| SCHEMBL1523741 | 0.67 | AKR1C3 (0.48) | AKR1C2PTGS1AKR1C3KDM4EPOLB | |
| SCHEMBL1523640 | 0.67 | AKR1C3 (0.48) | AKR1C2HSD17B10PTGS1AKR1C3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560827-B1 | ANTI-INFECTIVE AGENTS | ABBOTT LAB (US) | 2010-12-29 | — | — | EP | disclosed |
| EP-1560827-A1 | ANTI-INFECTIVE AGENTS | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | disclosed |
| US-20050075331-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2005-04-07 | — | — | US | disclosed |
| US-20040167123-A1 | Anti-infective agents | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
| WO-2004041818-A1 | ANTI-INFECTIVE AGENTS | ABBOTT LABORATORIES (US) | 2004-05-21 | — | — | WO | disclosed |
| US-20040087577-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162285-A1 | Anti-infective agents | POLR1C, RPL5, POLB | AKR1C2 2990/4885HSD17B10 1232/4885PTGS1 792/4885 |
| US-20040167123-A1 | Anti-infective agents | SERPINB1, CYP51A1, ZC3HAV1 | AKR1C2 2357/4885HSD17B10 1422/4885PTGS1 88/4885 |
| US-20050075331-A1 | Anti-infective agents | RPL35, POLI, POLRMT | AKR1C2 2757/4885HSD17B10 1335/4885PTGS1 283/4885 |
| US-20040087577-A1 | Anti-infective agents | POLR1C, RPL5, POLB | AKR1C2 2990/4885HSD17B10 1232/4885PTGS1 792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.