Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13018307 | 1.00 | MAPT (0.56) | MAPTRXFP1SIGMAR1TAAR1SLC18A2 | |
| SCHEMBL13311947 | 1.00 | MAPT (0.56) | MAPTRXFP1SIGMAR1TAAR1SLC18A2 | |
| Hydrochloric Acid SCHEMBL3487964 | 0.98 | MAPT (0.54) | MAPTRXFP1SIGMAR1TAAR1SLC18A2 | |
| SCHEMBL7603758 | 0.98 | MAPT (0.53) | MAPTRXFP1SIGMAR1TAAR1SLC18A2 | |
| Hydrochloric Acid SCHEMBL8475325 | 0.97 | MAPT (0.51) | MAPTRXFP1SIGMAR1TAAR1SLC18A2 | |
| Hydrochloric Acid SCHEMBL8475327 | 0.97 | MAPT (0.51) | MAPTRXFP1SIGMAR1TAAR1SLC18A2 | |
| SCHEMBL3391414 | 0.94 | HSD17B10 (0.54) | MAPTRXFP1SIGMAR1TAAR1SLC18A2 | |
| SCHEMBL11235453 | 0.94 | HSD17B10 (0.54) | MAPTRXFP1SIGMAR1TAAR1SLC18A2 | |
| SCHEMBL13311943 | 0.94 | HSD17B10 (0.54) | MAPTRXFP1SIGMAR1TAAR1SLC18A2 | |
| Hydrochloric Acid SCHEMBL3487407 | 0.92 | HSD17B10 (0.53) | MAPTRXFP1SIGMAR1TAAR1SLC18A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10550201-B2 | Antibody-nanoparticle conjugates for the treatment of drug abuse | BIOVENTURES, LLC (US) | 2020-02-04 | — | — | US | disclosed |
| EP-2140263-B1 | HAPTEN COMPOUNDS AND COMPOSITIONS AND USES THEREOF | UNIV ARKANSAS (US) | 2017-01-04 | — | — | EP | disclosed |
| US-9303092-B2 | Methamphetamine-like hapten compounds, linkers, carriers and compositions and uses thereof | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2016-04-05 | — | — | US | disclosed |
| US-8853146-B2 | Hapten compounds and compositions and uses thereof | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2014-10-07 | — | — | US | disclosed |
| US-20130296537-A1 | METHAMPHETAMINE-LIKE HAPTEN COMPOUNDS, LINKERS, CARRIERS AND COMPOSITIONS AND USES THEREOF | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2013-11-07 | — | — | US | disclosed |
| EP-2032602-B1 | MONOCLONAL ANTIBODIES THAT SELECTIVELY RECOGNIZE METHAMPHETAMINE AND METHAMPHETAMINE LIKE COMPOUNDS | UNIV ARKANSAS (US) | 2013-03-27 | — | — | EP | disclosed |
| US-8299222-B2 | Methamphetamine-like hapten compounds, linkers, carriers and compositions and uses thereof | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2012-10-30 | — | — | US | disclosed |
| US-7858756-B2 | Monoclonal antibodies that selectively recognize methamphetamine and methamphetamine like compounds | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2010-12-28 | — | — | US | disclosed |
| US-20100143391-A1 | HAPTEN COMPOUNDS AND COMPOSITIONS AND USES THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2010-06-10 | — | — | US | disclosed |
| US-20100055126-A1 | METHAMPHETAMINE-LIKE HAPTEN COMPOUNDS, LINKERS, CARRIERS AND COMPOSITIONS AND USES THEREOF | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2010-03-04 | — | — | US | disclosed |
| EP-2140263-A1 | HAPTEN COMPOUNDS AND COMPOSITIONS AND USES THEREOF | Board of Trustees of the University of Arkansas (US) | 2010-01-06 | — | — | EP | disclosed |
| US-7632929-B2 | Methamphetamine-like hapten compounds, linkers, carriers and compositions and uses thereof | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2009-12-15 | — | — | US | disclosed |
| EP-2032602-A2 | MONOCLONAL ANTIBODIES THAT SELECTIVELY RECOGNIZE METHAMPHETAMINE AND METHAMPHETAMINE LIKE COMPOUNDS | The Board of Trustees of the University of Arkansas System (US) | 2009-03-11 | — | — | EP | disclosed |
| WO-2008131216-A1 | HAPTEN COMPOUNDS AND COMPOSITIONS AND USES THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2008-10-30 | — | — | WO | disclosed |
| US-20080125579-A1 | MONOCLONAL ANTIBODIES THAT SELECTIVELY RECOGNIZE METHAMPHETAMINE AND METHAMPHETAMINE LIKE COMPOUNDS | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2008-05-29 | — | — | US | disclosed |
| WO-2007147122-A2 | MONOCLONAL ANTIBODIES THAT SELECTIVELY RECOGNIZE METHAMPHETAMINE AND METHAMPHETAMINE LIKE COMPOUNDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2007-12-21 | — | — | WO | disclosed |
| US-20070238653-A1 | METHAMPHETAMINE-LIKE HAPTEN COMPOUNDS, LINKERS, CARRIERS AND COMPOSITIONS AND USES THEREOF | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2007-10-11 | — | — | US | disclosed |
| US-20030119083-A1 | Monoclonal antibody antagonists for treating medical problems associated with d-amphetamine-like drugs | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125579-A1 | MONOCLONAL ANTIBODIES THAT SELECTIVELY RECOGNIZE METHAMPHETAMINE AND METHAMPHETAMINE LIKE COMPOUNDS | MAG, PNMT, MAP2 | MAPT 30/4885RXFP1 4392/4885SIGMAR1 759/4885 |
| US-20130296537-A1 | METHAMPHETAMINE-LIKE HAPTEN COMPOUNDS, LINKERS, CARRIERS AND COMPOSITIONS AND USES THEREOF | DDT, MAG, TAAR5 | MAPT 35/4885RXFP1 3832/4885SIGMAR1 600/4885 |
| US-20100055126-A1 | METHAMPHETAMINE-LIKE HAPTEN COMPOUNDS, LINKERS, CARRIERS AND COMPOSITIONS AND USES THEREOF | DDT, MAG, TAAR5 | MAPT 35/4885RXFP1 3832/4885SIGMAR1 600/4885 |
| US-20030119083-A1 | Monoclonal antibody antagonists for treating medical problems associated with d-amphetamine-like drugs | PNMT, EPHA5, EPHB1 | MAPT 194/4885RXFP1 3129/4885SIGMAR1 55/4885 |
| US-20070238653-A1 | METHAMPHETAMINE-LIKE HAPTEN COMPOUNDS, LINKERS, CARRIERS AND COMPOSITIONS AND USES THEREOF | DDT, MAG, TAAR5 | MAPT 35/4885RXFP1 3832/4885SIGMAR1 600/4885 |
| US-10550201-B2 | Antibody-nanoparticle conjugates for the treatment of drug abuse | CES2, SLC6A3, OPRM1 | MAPT 31/4885RXFP1 4000/4885SIGMAR1 109/4885 |
| US-20100143391-A1 | HAPTEN COMPOUNDS AND COMPOSITIONS AND USES THEREOF | DDT, TAAR5, MLLT1 | MAPT 76/4885RXFP1 4166/4885SIGMAR1 515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.