Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DTYMK | P23919 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31338514 | 0.79 | MAPT (0.60) | DTYMKTSHRKDM4EGLAMEN1 | |
| SCHEMBL297769 | 0.79 | MAPT (0.60) | DTYMKTSHRKDM4EGLAMEN1 | |
| SCHEMBL4609556 | 0.78 | TSHR (0.54) | TSHRKDM4EGLAAKR1C3AKR1C2 | |
| SCHEMBL1873510 | 0.77 | ALDH1A1 (0.50) | KDM4EGLACDC25BMEN1KMT2A | |
| SCHEMBL6081366 | 0.75 | HCAR3 (0.54) | DTYMKTSHRKDM4EMEN1KMT2A | |
| SCHEMBL10527436 | 0.75 | ATM (0.43) | TSHRMEN1KMT2AMGLLATM | |
| SCHEMBL8742107 | 0.75 | TPMT (0.49) | TSHRKDM4EGLAMEN1KMT2A | |
| SCHEMBL8044893 | 0.74 | NPSR1 (0.61) | TSHRGLAMEN1KMT2AATM | |
| SCHEMBL7497984 | 0.74 | DTYMK (0.51) | DTYMKTSHRKDM4EGLAAKR1C3 | |
| SCHEMBL11551945 | 0.74 | PDE7A (0.44) | TSHRMEN1KMT2AATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112724349-A | Novel polymers and uses thereof | 立邦涂料（中国）有限公司 | 2021-04-30 | — | — | CN | claimed |
| US-20120270282-A1 | PENICILLIN-G ACYLASES | CODEXIS, INC. (US) | 2012-10-25 | — | — | US | claimed |
| US-8247192-B2 | Penicillin-G acylases | CODEXIS, INC. (US) | 2012-08-21 | — | — | US | claimed |
| US-20100143968-A1 | PENICILLIN-G ACYLASES | CODEXIS, INC. (US) | 2010-06-10 | — | — | US | claimed |
| WO-2010054319-A2 | PENICILLIN-G ACYLASES | CODEXIS, INC. (US) | 2010-05-14 | — | — | WO | claimed |
| US-12480111-B2 | Penicillin-G acylases | CODEXIS, INC. (US) | 2025-11-25 | — | — | US | disclosed |
| US-20250346882-A1 | PENICILLIN-G ACYLASES | CODEXIS, INC. (US) | 2025-11-13 | — | — | US | disclosed |
| US-12378541-B2 | Penicillin-G acylases | CODEXIS, INC. (US) | 2025-08-05 | — | — | US | disclosed |
| US-20250034543-A1 | PENICILLIN-G ACYLASES | CODEXIS INC (US) | 2025-01-30 | — | — | US | disclosed |
| US-20240409916-A1 | PENICILLIN-G ACYLASES | CODEXIS INC (US) | 2024-12-12 | — | — | US | disclosed |
| US-12084697-B2 | Penicillin-G acylases | CODEXIS, INC. (US) | 2024-09-10 | — | — | US | disclosed |
| CN-110506113-B | Penicillin G acylase | 科德克希思公司 | 2024-05-03 | — | — | CN | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| EP-0961825-A1 | MUTANT PENICILLIN G ACYLASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-12-08 | — | — | EP | disclosed |
| WO-1998020120-A1 | MUTANT PENICILLIN G ACYLASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-14 | — | — | WO | disclosed |
| EP-0557509-A4 | — | — | 1994-02-09 | — | — | EP | disclosed |
| EP-0557509-A1 | MACROPOROUS POLYMERIC PARTICLES AS BIOCOMPATIBLE SUPPORTS | INTERACTION CHROMATOGRAPHY INC. (US) | 1993-09-01 | — | — | EP | disclosed |
| WO-1993006161-A1 | MACROPOROUS POLYMERIC PARTICLES AS BIOCOMPATIBLE SUPPORTS | INTERACTION CHROMATOGRAPHY INC. (US) | 1993-04-01 | — | — | WO | disclosed |
| US-5168104-A | Suspension polymerization and crosslinking of addition polymer in presence of inorganic particles filled with blowing agent; dissolving particles | CHEMBIOMED, LTD. (CA) | 1992-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270282-A1 | PENICILLIN-G ACYLASES | PGLS, PNP, NAAA | DTYMK 155/4885TSHR 4126/4885KDM4E 1645/4885 |
| US-20250034543-A1 | PENICILLIN-G ACYLASES | NAAA, PGLS, PNP | DTYMK 168/4885TSHR 4074/4885KDM4E 1547/4885 |
| US-20240409916-A1 | PENICILLIN-G ACYLASES | NAAA, PGLS, PNP | DTYMK 184/4885TSHR 3862/4885KDM4E 1732/4885 |
| US-12084697-B2 | Penicillin-G acylases | NAAA, PGLS, PNP | DTYMK 184/4885TSHR 3862/4885KDM4E 1732/4885 |
| US-20100143968-A1 | PENICILLIN-G ACYLASES | PGLS, PNP, NAAA | DTYMK 155/4885TSHR 4126/4885KDM4E 1645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.