Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9065449 | 0.77 | — | — | |
| SCHEMBL184093 | 0.76 | ALOX15 (0.39) | MMP8ALOX15MEN1CYP3A4KMT2A | |
| SCHEMBL184094 | 0.76 | ALOX15 (0.39) | MMP8ALOX15MEN1CYP3A4KMT2A | |
| SCHEMBL545025 | 0.72 | — | — | |
| SCHEMBL28703110 | 0.72 | — | — | |
| SCHEMBL7559297 | 0.70 | — | — | |
| SCHEMBL11849474 | 0.70 | MEN1 (0.35) | MMP8ALOX15MEN1CYP3A4KMT2A | |
| SCHEMBL12673069 | 0.70 | MEN1 (0.35) | MMP8ALOX15MEN1CYP3A4KMT2A | |
| SCHEMBL11849468 | 0.70 | MEN1 (0.35) | MMP8ALOX15MEN1CYP3A4KMT2A | |
| SCHEMBL1782690 | 0.69 | MMP8 (0.37) | MMP8ALOX15MEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056636-A1 | N-Substituted-P-Menthane-3-Carboxamide and Uses Thereof | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2010-03-04 | — | — | US | disclosed |
| EP-2104436-A1 | N-SUBSTITUTED-P-MENTHANE-3-CARBOXAMIDE AND USES THEREOF | Givaudan Nederland Services B.V. (NL) | 2009-09-30 | — | — | EP | disclosed |
| WO-2008075942-A1 | N-SUBSTITUTED-P-MENTHANE-3-CARBOXAMIDE AND USES THEREOF | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2008-06-26 | — | — | WO | disclosed |
| US-4366317-A | Process for synthesis of N-(hydrocarbyl)substituted-p-menthane-3-carboxamide | PHILIP MORRIS INCORPORATED (US) | 1982-12-28 | — | — | US | disclosed |
| US-4350832-A | Synthesis of N-t-butyl-p-menthane-3-carboxamide | PHILIP MORRIS, INCORPORATED (US) | 1982-09-21 | — | — | US | disclosed |
| US-4318900-A | STIMULANTS | WILKINSON SWORD LIMITED (GB) | 1982-03-09 | — | — | US | disclosed |
| US-4248859-A | USED IN EDIBLE AND TOPICAL PREPARATIONS | WILKINSON SWORD LIMITED (GB) | 1981-02-03 | — | — | US | disclosed |
| US-4226988-A | SKIN COOLANTS | WILKINSON SWORD LIMITED (GB) | 1980-10-07 | — | — | US | disclosed |
| US-4193936-A | N-substituted paramenthane carboxamides | WILKINSON SWORD LIMITED (GB) | 1980-03-18 | — | — | US | disclosed |
| US-4190643-A | P-METHANE-3-CARBOXAMIDES STIMULANTS | WILKINSON SWORD LIMITED (GB) | 1980-02-26 | — | — | US | disclosed |
| US-4178459-A | N-Substituted paramenthane carboxamides | WILKINSON SWORD LIMITED (GB) | 1979-12-11 | — | — | US | disclosed |
| US-4157384-A | Compositions having a physiological cooling effect | WILKINSON SWORD LIMITED (GB) | 1979-06-05 | — | — | US | disclosed |
| US-4150052-A | PHYSIOLOGICAL COOLING EFFECT ON SKIN | WILKINSON SWORD LIMITED (GB) | 1979-04-17 | — | — | US | disclosed |
| US-4137305-A | TOBACCO | WILKINSON SWORD LIMITED (GB) | 1979-01-30 | — | — | US | disclosed |
| US-4137304-A | TOPICAL OR ORAL ADMINISTERED TOBACCO PRODUCT | WILKINSON SWORD LIMITED (GB) | 1979-01-30 | — | — | US | disclosed |
| US-4136163-A | P-MENTHANE CARBOXAMIDES HAVING A PHYSIOLOGICAL COOLING EFFECT | WILKINSON SWORD LIMITED (GB) | 1979-01-23 | — | — | US | disclosed |
| US-4136164-A | FOR USE IN FOODS, TOPICAL PREPARATIONS, AND TOBACCO | WILKINSON SWORD LIMITED (GB) | 1979-01-23 | — | — | US | disclosed |
| US-4060091-A | N-SUBSTITUTED P-MENTHANE CARBOXAMID | WILKINSON SWORD LIMITED (EN) | 1977-11-29 | — | — | US | disclosed |
| US-4059118-A | MENTHANE DERIVATIVE | WILKINSON SWORD LIMITED (EN) | 1977-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056636-A1 | N-Substituted-P-Menthane-3-Carboxamide and Uses Thereof | ME2, NAPEPLD, TRPM7 | MMP8 2519/4885ALOX15 1339/4885MEN1 779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.