Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11097893 | 0.77 | TDP1 (0.48) | TRPA1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL874253 | 0.75 | HTT (0.62) | TRPA1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL6421123 | 0.73 | MAPK1 (0.52) | TRPA1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL7353270 | 0.73 | ALDH1A1 (0.49) | TRPA1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL3931538 | 0.72 | MAPT (0.50) | TRPA1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL11569642 | 0.72 | KMT2A (0.44) | MEN1KMT2AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL5491118 | 0.72 | TDP1 (0.43) | TRPA1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL11867244 | 0.71 | MEN1 (0.46) | TRPA1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL7297638 | 0.71 | MAPT (0.48) | TRPA1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL11326501 | 0.70 | MAPT (0.49) | MEN1KMT2AMAPTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560558-B1 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2010-12-29 | — | — | EP | claimed |
| EP-1560558-A4 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2008-09-24 | — | — | EP | claimed |
| JP-2006508103-A | — | — | 2006-03-09 | — | — | JP | claimed |
| US-6987090-B2 | Use of 3-position cyclosporin derivatives for hair growth | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2006-01-17 | — | — | US | claimed |
| EP-1560558-A1 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG Household & Health Care Ltd. (KR) | 2005-08-10 | — | — | EP | claimed |
| WO-2004041221-A1 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2004-05-21 | — | — | WO | claimed |
| US-20040087496-A1 | Use of 3-position cyclosporin derivatives for hair growth | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2004-05-06 | — | — | US | claimed |
| EP-1560558-B1 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2010-12-29 | — | — | EP | disclosed |
| EP-1560558-A4 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2008-09-24 | — | — | EP | disclosed |
| US-6987090-B2 | Use of 3-position cyclosporin derivatives for hair growth | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2006-01-17 | — | — | US | disclosed |
| EP-1560558-A1 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG Household & Health Care Ltd. (KR) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004041221-A1 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2004-05-21 | — | — | WO | disclosed |
| US-20040087496-A1 | Use of 3-position cyclosporin derivatives for hair growth | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087496-A1 | Use of 3-position cyclosporin derivatives for hair growth | TPMT, BHMT2, SUCLG1 | TRPA1 3189/4885MEN1 4071/4885KMT2A 2753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.