Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13426524 | 0.82 | MAPT (0.47) | PDE4BPDE4DRAD51MAPTMEN1 | |
| SCHEMBL3396698 | 0.81 | GABRA1 (0.44) | RAD51MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL3399530 | 0.79 | PTGS2 (0.49) | PDE4BMAPTMEN1KMT2ARAB9A | |
| SCHEMBL3400232 | 0.75 | PHGDH (0.43) | MAPTMEN1KMT2AALDH1A1PHGDH | |
| SCHEMBL3395570 | 0.72 | MAPT (0.47) | MAPT | |
| SCHEMBL10665356 | 0.72 | SMN1; SMN2 (0.53) | PDE4BMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8471355 | 0.72 | PHGDH (0.49) | RAD51MAPTMEN1KMT2ARAB9A | |
| SCHEMBL18127956 | 0.72 | SCN4A (0.65) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL11157691 | 0.71 | MCL1 (0.60) | RAD51MAPTMEN1KMT2ARAB9A | |
| SCHEMBL874933 | 0.71 | PHGDH (0.52) | RAD51MAPTMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |