Carbamic Acid

Carbamic Acid

SCHEMBL3394720

NC(=O)O.OCC(O)c1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.58
AOC3 Q16853 5/20 0.50
LMNA P02545 4/20 0.50
KDM4E B2RXH2 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
MAPK1 P28482 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
PKM P14618 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
EPHX1 P07099 1/20 0.46
SLC6A3 Q01959 2/20 0.44
ADORA3 P0DMS8 1/20 0.44
EDNRB P24530 1/20 0.44
MC4R P32245 1/20 0.44
CYP2C19 P33261 1/20 0.44
DRD3 P35462 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL6362690 1.00 BCAT2 (0.58) BCAT2AOC3LMNAKDM4EL3MBTL1
Bicarbonate SCHEMBL2836236 0.91 LMNA (0.54) BCAT2AOC3LMNAKDM4EL3MBTL1
SCHEMBL30957022 0.89 LMNA (0.61) BCAT2AOC3LMNAKDM4EL3MBTL1
SCHEMBL24750 0.89 LMNA (0.61) BCAT2AOC3LMNAKDM4EL3MBTL1
SCHEMBL1947849 0.89 LMNA (0.61) BCAT2AOC3LMNAKDM4EL3MBTL1
SCHEMBL3413766 0.89 LMNA (0.61) BCAT2AOC3LMNAKDM4EL3MBTL1
SCHEMBL8366350 0.89 LMNA (0.61) BCAT2AOC3LMNAKDM4EL3MBTL1
SCHEMBL29588786 0.86 LMNA (0.58) BCAT2AOC3LMNAKDM4EL3MBTL1
SCHEMBL18813398 0.86 LMNA (0.58) BCAT2AOC3LMNAKDM4EL3MBTL1
SCHEMBL27887405 0.86 LMNA (0.58) BCAT2AOC3LMNAKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0907635-B1 HALOGEN SUBSTITUTED CARBAMATE COMPOUNDS FROM 2-PHENYL-1,2-ETHANEDIOL SK CORP (KR) 2002-09-25 EP claimed
US-5854283-A Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol YUKONG LIMITED (KR) 1998-12-29 US claimed
EP-1404312-B1 CARBAMATE COMPOUNDS FOR USE IN THE TREATMENT OF PAIN ORTHO MCNEIL PHARM INC (US) 2010-12-29 EP disclosed
CN-101568362-A Methods for treating depression JANSSEN PHARMACEUTICA NV (BE) 2009-10-28 CN disclosed
US-20090234003-A1 CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING ANXIETY DISORDERS PLATA-SALAMAN CARLOS R 2009-09-17 US disclosed
US-20090005442-A1 CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING NEURODEGENERATIVE DISORDERS SK BIOPHARMACEUTICALS CO., LTD (KR) 2009-01-01 US disclosed
EP-1411917-B1 CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING MOVEMENT DISORDERS ORTHO MCNEIL PHARM INC (US) 2007-08-08 EP disclosed
EP-1383489-B1 CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING NEURODEGENERATIVE DISORDERS ORTHO MCNEIL PHARM INC (US) 2007-05-09 EP disclosed
EP-1401424-B1 CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING PSYCHOTIC DISORDERS ORTHO MCNEIL PHARM INC (US) 2006-11-29 EP disclosed
US-7078436-B2 Carbamate compounds for use in preventing or treating anxiety disorders ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2006-07-18 US disclosed
EP-1399144-B1 CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING ANXIETY DISORDERS ORTHO MCNEIL PHARM INC (US) 2006-04-26 EP disclosed
US-20020156127-A1 Carbamate compounds for use in the treatment of pain SK BIOPHARMACEUTICALS CO., LTD (KR) 2002-10-24 US disclosed
US-20020151585-A1 Carbamate compounds for use in preventing or treating movement disorders SK BIOPHARMACEUTICALS CO., LTD (KR) 2002-10-17 US disclosed
US-20020143053-A1 Carbamate compounds for use in preventing or treating anxiety disorders ORTHO-MCNEIL PHARMACEUTICAL, INC. 2002-10-03 US disclosed
WO-2002067927-A1 CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING PSYCHOTIC DISORDERS ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2002-09-06 WO disclosed
WO-2002067926-A1 CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING MOVEMENT DISORDERS ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2002-09-06 WO disclosed
WO-2002067925-A1 CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING NEURODEGENERATIVE DISORDERS ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2002-09-06 WO disclosed
WO-2002067923-A1 CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING ANXIETY DISORDERS ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2002-09-06 WO disclosed
WO-2002067922-A1 CARBAMATE COMPOUNDS FOR USE IN THE TREATMENT OF PAIN ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2002-09-06 WO disclosed
US-5698588-A OPTICALLY PURE ENANTIOMERIC FORM; TREATING CENTRAL NERVOUS SYSTEM DISORDERS YUKONG LIMITED (KR) 1997-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020156127-A1 Carbamate compounds for use in the treatment of pain CNR1, CBR3, CNR2 BCAT2 623/4885AOC3 403/4885LMNA 3944/4885
US-20090005442-A1 CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING NEURODEGENERATIVE DISORDERS BCHE, CBR3, C9 BCAT2 493/4885AOC3 27/4885LMNA 1544/4885
US-20090234003-A1 CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING ANXIETY DISORDERS CBR3, CBR1, CNR1 BCAT2 208/4885AOC3 49/4885LMNA 1908/4885
US-20020151585-A1 Carbamate compounds for use in preventing or treating movement disorders CHAT, CES2, SLC6A3 BCAT2 411/4885AOC3 110/4885LMNA 2953/4885
US-20020143053-A1 Carbamate compounds for use in preventing or treating anxiety disorders CBR1, CNR1, CBR3 BCAT2 149/4885AOC3 115/4885LMNA 2475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.