Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 3/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042133 | 0.76 | — | — | |
| SCHEMBL4452908 | 0.71 | CYP1A2 (0.45) | TAAR1PDK2CES1MEN1KMT2A | |
| SCHEMBL18274985 | 0.71 | CES2 (0.39) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL14747016 | 0.69 | THRB (0.44) | TAAR1GAACA1CA2PBRM1 | |
| SCHEMBL18789227 | 0.69 | ALDH1A1 (0.65) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL530880 | 0.69 | — | — | |
| SCHEMBL22030439 | 0.69 | MEN1 (0.39) | NPC1RAB9ATTRPDK2CES2 | |
| SCHEMBL30264722 | 0.69 | — | — | |
| SCHEMBL11304580 | 0.69 | NR1H2 (0.35) | PDK2MEN1KMT2A | |
| SCHEMBL22129686 | 0.67 | CA1 (0.48) | NPC1RAB9ATTRPDK2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164901-A2 | MIXTURES OF POLYDIORGANOSILOXANE POLYAMIDE-CONTAINING COMPONENTS AND ORGANIC POLYMERS | 3M Innovative Properties Company (US) | 2010-03-24 | — | — | EP | disclosed |
| EP-2162485-A1 | BRANCHED POLYDIORGANOSILOXANE POLYAMIDE COPOLYMERS | 3M Innovative Properties Company (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2009002666-A1 | POLYDIORGANOSILOXANE POLYOXAMIDE COPOLYMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009002611-A1 | BRANCHED POLYDIORGANOSILOXANE POLYAMIDE COPOLYMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009002668-A2 | MIXTURES OF POLYDIORGANOSILOXANE POLYAMIDE-CONTAINING COMPONENTS AND ORGANIC POLYMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-12-31 | — | — | WO | disclosed |