Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | FPR1 | P21462 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | C1S | P09871 | 1/20 | 0.41 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21610736 | 0.98 | RAB9A (0.44) | MAPK1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5708677 | 0.94 | RAB9A (0.44) | MAPK1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8003695 | 0.90 | — | — | |
| SCHEMBL22448993 | 0.88 | ALDH1A1 (0.41) | MAPK1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8256801 | 0.82 | MAPT (0.45) | MAPK1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL22860589 | 0.81 | HRH4 (0.42) | MAPK1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10194544 | 0.81 | RAB9A (0.44) | MAPK1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2671753 | 0.81 | RAB9A (0.44) | MAPK1RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1801634 | 0.76 | HSD17B10 (0.51) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9891489 | 0.76 | TMIGD3 (0.42) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020002090-A1 | SUBSTITUTED THIAZOLYLPYRROLONES, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-01-02 | — | — | WO | disclosed |
| US-20170334912-A1 | Purine Diones As Wnt Pathway Modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-11-23 | — | — | US | disclosed |
| EP-2748150-B1 | HIV REPLICATION INHIBITORS | SOUTHERN RES INST (US) | 2016-11-30 | — | — | EP | disclosed |
| US-9120787-B2 | HIV replication inhibitors | SOUTHERN RESEARCH INSTITUTE (US) | 2015-09-01 | — | — | US | disclosed |
| US-9120787-B2 | HIV replication inhibitors | SOUTHERN RESEARCH INSTITUTE (US) | 2015-09-01 | — | — | US | disclosed |
| US-20140235582-A1 | HIV REPLICATION INHIBITORS | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2014-08-21 | — | — | US | disclosed |
| US-20140235582-A1 | HIV REPLICATION INHIBITORS | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2014-08-21 | — | — | US | disclosed |
| WO-2013033003-A1 | HIV REPLICATION INHIBITORS | SOUTHERN RESEARCH INSTITUTE (US) | 2013-03-07 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334912-A1 | Purine Diones As Wnt Pathway Modulators | WNT1, WNT3A, CTNNB1 | MAPK1 920/4885RAB9A 3162/4885NPC1 2489/4885 |
| US-20140235582-A1 | HIV REPLICATION INHIBITORS | RTF2, POLR2H, POLR2E | MAPK1 1913/4885RAB9A 2014/4885NPC1 1584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.