Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 6/20 | 0.59 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392207 | 0.85 | PRMT1 (0.62) | PRMT1SCN10AABCB1PRMT6SLC6A4 | |
| SCHEMBL3395465 | 0.85 | SLC6A4 (0.47) | PRMT6SLC6A4TSHRSERPINE1ACHE | |
| SCHEMBL3398483 | 0.78 | ERCC5 (0.39) | PRMT1PRMT6SLC6A4PTGER4SERPINE1 | |
| SCHEMBL3709650 | 0.76 | PRMT1 (0.51) | PRMT1SCN10AABCB1PRMT6HTR6 | |
| Hydrochloric Acid SCHEMBL3398629 | 0.75 | PRMT1 (0.52) | PRMT1SCN10AABCB1PRMT6TSHR | |
| SCHEMBL13074386 | 0.74 | SLC6A4 (0.57) | PRMT1PRMT6SLC6A4TSHRSERPINE1 | |
| Trifluoroacetic Acid SCHEMBL3398116 | 0.74 | PRMT1 (0.47) | PRMT1SCN10AABCB1PTGER4SERPINE1 | |
| SCHEMBL3398119 | 0.73 | PRMT1 (0.46) | PRMT1SCN10AABCB1PTGER4SERPINE1 | |
| SCHEMBL22042121 | 0.71 | PRMT1 (0.54) | PRMT1SCN10AABCB1MCHR1 | |
| SCHEMBL3397309 | 0.71 | SLC6A4 (0.36) | PRMT6SLC6A4ACHELSSPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246329-A1 | 4(1H)-pyridinone derivatives and their use as antimalaria agents | Glaxo Group Limited (GB) | 2010-11-03 | — | — | EP | disclosed |